Contract SAS Programmer (Gene Therapy - Ophthalmology)
Join to apply for the Contract SAS Programmer (Gene Therapy - Ophthalmology) role at AAVantgarde Bio.
** PLEASE NOTE: This is a contract position. We are able to offer this at either 50% capacity (~20 hours per week) or 100% capacity (~40 hours per week) **
The Company
AAVantgarde is a clinical-stage, international biotechnology company headquartered in Italy. We have developed two cutting-edge AAV vector platforms to overcome DNA cargo limitations, targeting Usher syndrome type 1B and Stargardt disease. Founded by the renowned Professor Alberto Auricchio, a pioneer in gene therapy, our mission is to transform genetic medicine for patients with no current therapeutic options.
The Role
We are seeking a highly experienced and hands-on Principal SAS Programmer to join our team in support of a cutting-edge gene therapy clinical trial program in ophthalmology. This role involves advanced programming, data management, and process optimization. The ideal candidate will have a strong background in SAS programming, CDISC standards, and clinical trial data analysis.
In this role, you will provide expert-level programming support for our gene therapy ophthalmology program, creating and maintaining SAS programs to clean, analyze, and report clinical trial data. Ensuring that all programming and reporting follow CDISC standards, particularly SDTM and ADaM, will be paramount. You will actively contribute to the development and execution of SAS programs to derive analysis datasets, tables, listings, and figures for clinical study reports (CSRs) and regulatory submissions.
Leading efforts to ensure data integrity and consistency throughout the clinical trial, you will develop validation checks, data cleaning scripts, and identify and resolve data discrepancies. Your role will also involve providing technical leadership and mentorship to junior programming staff. Additionally, you will support the preparation of datasets and programming outputs required for regulatory submissions.
Skills and experience required
The ideal candidate will possess a Bachelor's or Master's degree in a related field, such as Life Sciences, Computer Science, or Mathematics. You should have a minimum of 8-10 years of experience in SAS programming within the clinical trials environment, with significant experience in gene therapy and ophthalmology clinical trials. Strong expertise in CDISC SDTM and ADaM standards, including the creation, manipulation, and validation of datasets for regulatory submissions, is essential.
Proven expertise in SAS programming for clinical trial data analysis and reporting, deep knowledge of CDISC standards, and experience in preparing data for regulatory submission to bodies like the FDA and EMA are crucial. A strong understanding of clinical trial design, particularly in ophthalmology and gene therapy, is also required.
What's in it For You
At AAVantgarde, we believe in creating an environment where our employees can thrive. Our flexible working environment allows you to balance work and life effectively. We offer a generous salary, bonus, pension, health insurance through Vitality, and income protection.
At AAVantgarde, we are committed to fostering a welcoming, collaborative, and inclusive environment. We believe in providing equal opportunities for all and do not discriminate on the basis of race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or any other legally protected characteristics.
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