Organisation/Company: KINGS COLLEGE LONDON
Research Field: Other
Researcher Profile: Recognised Researcher (R2), First Stage Researcher (R1)
Country: United Kingdom
Application Deadline: 18 Mar 2025 - 00:00 (UTC)
Type of Contract: Other
Job Status: Full-time
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer Description
About us
Dementia is one of the greatest health challenges of our century. To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
We are a globally leading multidisciplinary research institute of 850 staff investigating the spectrum of neurodegenerative disorders causing dementia, with laboratory-based research groups located at University College London, the University of Cambridge, Cardiff University, Edinburgh University, Imperial College London, and King’s College London.
Researchers at the UK DRI at King’s use innovative approaches to explore the biological mechanisms involved in neurodegenerative diseases. Their goal is to defeat dementia by uncovering vital new knowledge that will lead to the design of smarter diagnostics and effective treatments.
About the role
A new position is available for an experienced Research Assistant in the UK Dementia Research Institute (UK DRI) research group led by Dr Sarah Marzi. The group is seeking an organised and enthusiastic individual for a full-time research assistant position to support their research.
This position will involve significant molecular biology laboratory work, including gene expression and RNA-sequencing analysis by next generation sequencing, single cell approaches and nanopore sequencing, mammalian cell culture, and stem cell culture. It requires consistency and attention to detail, as well as a willingness for occasional weekend work in the context of cellular work. The post-holder will also provide support for general organisational and technical duties to allow the smooth and efficient running of the lab.
Dr Marzi’s group aims to determine the role of epigenetic regulation in neurodegenerative diseases, including ALS, Parkinson’s and Alzheimer’s disease, using state of the art epigenetic and genomic techniques in cell populations and at the single cell level.
About you
To be successful in this role, we are looking for candidates to have the following skills and experience:
* Experience in cell culture, including human iPSC cell culture
* Experience with single cell/nuclear genomic approaches
* Experience working with human post-mortem brain tissue
* Experience with fluorescence activated cell or nuclear sorting
* Knowledge of epigenetics and gene regulation
* Knowledge of basic neuroscience and neurodegenerative diseases
* An interest in the mission and research of the UK Dementia Research Institute
Further information
We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.
We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.
We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert.
This post is subject to an Occupational Health clearance.
Grade and Salary: £38,232 - £39,866 per annum, including London Weighting Allowance
Job ID: 109945
Close Date: 18-Mar-2025
Contact Person: Dr Sarah Marzi
Contact Details: Sarah.marzi@kcl.ac.uk
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