Senior Scientist - Tissue profiling
London
About Relation
Relation is an end-to-end biotech company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays, and machine learning to drive disease understanding—from cause to cure.
This year, we embarked on an exciting dual collaboration with GSK to tackle fibrosis and osteoarthritis, while also advancing our own internal osteoporosis programme. By combining our cutting-edge ML capabilities with GSK’s deep expertise in drug discovery, this partnership underscores our commitment to pioneering science and delivering impactful therapies to patients.
We are rapidly scaling our technology and discovery teams, offering a unique opportunity to join one of the most innovative TechBio companies. Be part of our dynamic, interdisciplinary teams, collaborating closely to redefine the boundaries of possibility in drug discovery. Our state-of-the-art wet and dry laboratories, located in the heart of London, provide an exceptional environment to foster interdisciplinarity and turn groundbreaking ideas into impactful therapies for patients.
We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the grounds of gender, sexual orientation, marital or civil partner status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. We cultivate innovation through collaboration, empowering every team member to do their best work and reach their highest potential.
By joining Relation, you will become part of an exceptionally talented team with extraordinary leverage to advance the field of drug discovery. Your work will shape our culture, strategic direction, and, most importantly, impact patients’ lives.
Opportunity
Relation has an excellent opportunity for a Senior Scientist to join an interdisciplinary, highly collaborative team of experimental and computational drug discovery researchers in our newly built state-of-the-art functional genomics lab in London.
At Relation, as a Senior Scientist specialising in single-cell processes and spatial biology, you will play a critical role in advancing our drug discovery pipeline. Your work will be integral to our clinical studies, translating laboratory findings into potential therapeutic applications. You will be responsible for designing and executing experiments that uncover cellular mechanisms, analyse spatial organisation, and identify novel therapeutic targets. This role combines hands-on laboratory work with cross-functional team collaboration, allowing you to work closely with experts in various disciplines to drive innovative solutions and further the development of new treatments.
Your responsibilities
* Design, implement, and optimize experiments in single-cell technologies and spatial biology platforms (e.g., spatial transcriptomics, multiplex imaging).
* Develop and implement protocols to enhance experimental efficiency and reproducibility.
* Perform bench work, including sample preparation, instrument operation, and troubleshooting.
* Test and evaluate new technologies and workflows to stay at the cutting edge of the field.
* Provide guidance and technical expertise to junior scientists and research associates.
* Maintain accurate and detailed records of experiments and results.
* Help and support the team with biobanking when necessary.
* Contribute to the development and writing of standard operating procedures (SOPs).
* Ensure the laboratory is clean, organised, and compliant with safety and operational standards by taking part in housekeeping duties and writing risk assessments, while also maintaining laboratory equipment and managing the inventory of reagents and consumables.
* Maintain laboratory equipment and inventory of reagents and consumables.
Professionally, you have
* A PhD and at least 3 years additional experience with an outstanding track record in academia, biotech or pharma.
* At least three years of research experience in applying spatial biology approaches to tissues, including handling fresh tissue and for FFPE (spatial transcriptomics and protein-based methods as well as IHC).
* Experience in spatial proteomics panel design for Immunofluorescence.
* At least two years of research experience in applying single-cell transcriptomics approaches to different cell types and tissues.
* Expertise in preparation of NGS library preparation and Illumina sequencing.
* A proven ability to deliver to tight timelines.
Desirable knowledge or experiences
* Experience in the preparation of soft, fibrotic, and hard tissues for single-cell methods (tissue dissociation).
* Experience with FACS.
* Experience in liquid handling or automation.
* Experience with cell culture.
* Experience of interdisciplinary team-working, especially with computational and machine learning scientists.
Personally, you are
* A highly motivated, independent self-starter and problem-solver.
* Exceptionally organised with a strong attention to detail, capable of learning quickly and working efficiently under pressure and shifting priorities.
* Able to communicate effectively with scientists across various disciplines.
* Skilled in building effective working relationships, demonstrating proven teamwork abilities.
* Inclusive in your approach with a naturally inquisitive mindset.
* Driven by a passion for applying cutting-edge single-cell and spatial technologies to identify disease risk genes and drug targets for conditions with unmet needs.
Join us in this exciting role, where your contributions will directly impact advancing our understanding of genetics and disease risk, supporting our mission to deliver transformative medicines to patients. Together, we’re not just conducting research—we’re setting new standards in the fields of machine learning and genetics. The patient is waiting!
Relation is a committed equal opportunities employer.
RECRUITMENT AGENCIES: Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs.
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