Job Title: Senior Scientist - Large Molecule Discovery
We are currently seeking an enthusiastic and self-motivated Senior Scientist to join a global pharmaceutical company for an initial 12-month contract. This exciting opportunity offers up to £27 p/h and is an integral part of the Large Molecule Discovery team, where you will be working at the forefront of biopharmaceutical research. As part of this dynamic team, you will contribute to the discovery and development of novel biopharmaceutical medicines.
Role Responsibilities:
* Run high throughput methods to predict in vitro antibody characteristics during exposure in vivo, using techniques such as chromatography-based analytical methods (SEC-HPLC, CIEX-HPLC), ELISA, and flow-based methods.
* Design, qualify, and execute experiments to characterise antibody panels, including non-specific binding measurements using flow cytometry and ELISA methods.
* Plan, design, and execute experiments to enable key decisions for project progression.
* Work independently to analyze and interpret data, providing clear recommendations to project teams..
* Collaborate in matrix teams, delivering objectives within agreed timelines.
* Keep up to date with relevant literature and new technologies, demonstrating exemplary scientific habits.
* Develop and implement high throughput methods for antibody characteristic prediction during exposure in vivo.
* Ensure adherence to safety and company regulations, and maintain lab equipment and reagents as necessary.
Key Requirements:
* Degree in Biology, Biochemistry, Immunology, or other relevant disciplines.
* A track record of recent scientific success, supported by relevant post-degree experience in academic or industrial science.
* Competence in performing relevant analytical/biological research techniques, such as immunoassay, flow cytometry, and SEC-HPLC, ELISA.
* Knowledge of antibody structure and function.
* Experience in designing and using automated solutions for scientific workflows, including liquid handlers.
* Strong adaptability to new scientific areas and ability to collaborate across teams.
* Preferred: Good understanding of antibody clearance mechanisms and related concepts.