CMC Manager - Antibody Drug Conjugates - Cambridge UK - Hybrid
Are you passionate about advancing new therapeutics to patients? Are you a subject matter expert in Antibody Drug Conjugates (ADCs)? Are you constantly keeping up to date with advancements & platforms in ADCs?
If you said yes to the above, CSG have a great opportunity to join a growing pharma business as their CMC Manager - Antibody Drug Conjugates. You will be directly responsible for driving ADC programs through the IND/CMC process and into the clinic to treat individuals with cancer.
You will be:
* Driving ADCs through the IND process and into the clinic
* Supporting earlier stage programs as an expert in ADCs and working closely with research and discovery teams
* Providing scientific guidance to both internal teams and external partners (CDMOs)
* Selection and management of third party CDMOs for ADC partnerships
* Authoring and leading module 3 IND applications
* Providing expertise in Drug Antibody Ratios (DAR), conjugations, linkers, payloads and other specialist technical areas related to ADCs
* Advise and suggest improvements for technologies and monitoring the advancements in the field
* Acting as the expert within the wider business for ADCs for regulatory and analytical requirements
To be successful in this position you will have:
* A relevant PhD in life sciences related topic
* Considerable hands-on experience with ADCs including Drug Antibody Ratios, different conjugations, linkers and payloads etc
* Previous experience with authoring and leading IND submissions for ADCs
* A passion for improving process and deep technical knowledge of advancements in ADC technologies, systems and platforms
* Third party CDMO selection and management
* Understanding of quality and regulatory requirements to move ADCs into phase 1 trials
* Excellent scientific problem solving and decision making skills
This role is an excellent opportunity to join a fast-paced business looking to make huge strides in human health and bring innovative medicines to patients.
We are open to considering candidates who would be interested in relocation to the UK for this role. If you are interested in finding out more about this role - reach out or apply today