Job Title: Scientist/Sr. Scientist (Functional Genomics) Location: Durham, North Carolina Company Overview: Tavros Therapeutics is a precision oncology company that leverages next-generation functional and computational genomics technology to uncover unique vulnerabilities within tumors to discover novel targets and biomarkers in areas of high unmet clinical need. The company’s next generation, bi-directional synthetic lethality platform can precisely and directly identify the paired genetic interactions that form the basis for breakthrough targets and first-in-class cancer drugs. Our collaborative spirit isn't just a perk—it's why we've been honored with the 'Best Places to Work' award. With a diverse team where over 50% of our employees are women, we foster a supportive and dynamic environment that keeps turnover rates low. Job Overview: We are seeking a motivated and talented Scientist/Sr. Scientist with a strong background in genome engineering and tool building to join our tech development team in RTP, North Carolina. This role is crucial in driving the target identification and development of novel cancer drugs. The ideal candidate should be an expert in advanced CRISPR systems included cas-9, base editing and prime editing, and have a hands-on approach to building new platforms and tools. We seek a 'doer' who likes to tinker, someone who thrives on creating new capabilities and engaging with project teams on vector design and tool development. This role offers a unique opportunity to join a growing startup and make a significant impact in the field of precision oncology with a potential career path to Head of Tech Dev. Key Responsibilities: Build new platforms and tools, creating new capabilities in gene editing, and engage with project teams on vector design and tool development. Design and perform cutting-edge functional genomic experiments to develop and analyze novel drug targets, biomarkers, and mechanisms of action. Collaborate with computational biology for the design and analysis of functional genomics screens. Communicate scientific strategies effectively in internal meetings and contribute to advancing the company's discovery platform technology and small molecule pipeline. Stay up to date on scientific literature in the field and contribute to the overall growth of the company. Requirements: PhD in Cancer Biology, Biomedical Engineering, Molecular Biology, or a related field, or equivalent education and experience, with 1-5 years of relevant experience. Minimum of 2 years of advanced high-throughput functional genomics experience. Proven experience in molecular biology and cancer research, with strong hands-on technical laboratory skills. Proficient in molecular and cellular biology techniques such as cloning, PCR, RNA/DNA isolation, qPCR, and western blotting. Strong background in cancer drug discovery, with required benchwork responsibilities. Excellent written and oral communication skills, with attention to detail in documenting, executing, and analyzing experiments. Flexibility, initiative to tackle new tasks, and ability to work closely with team members. Ideal Research Interests: Engineering and evolution of genome editing proteins such as base editors for genetic disease treatment. Evolution of proteins with therapeutic potential using phage-assisted continuous evolution (PACE). Discovery of bioactive synthetic small molecules and polymers using DNA-templated organic synthesis and DNA-encoded libraries.