Touchlight is focussed on the enzymatic synthesis of novel DNA formats.
This quiet revolution has been propelled into the spotlight with the scale-up and proof of concept of RNA and DNA based vaccines.
Our CDMO and technology is built on the conviction that DNA is fundamental to the future of medicine.
By moving away from today's restrictive biological approaches, we have made DNA manufacturing simple.
Our unique dbDNATM (or "doggybone" DNA) vector is optimised for use in advanced genetic medicines, being safer and more efficacious than conventional plasmid DNA.
The platform, based on enzymatic technology, enables DNA production at unprecedented scale, speed and purity.
We are leveraging our platform to enable the next generation of Genetic Medicines.
Our CDMO Focus is on:
* Nucleic Acid Medicines (mRNA & DNA)
* ex-vivo & in-vivo cell and genetic medicines
* Gene therapy using viral vectors and gene editing
* Autologous & Allogenic cell therapy
You will genetically engineer the DNA starting material for dbDNATM.
This is an exciting, fast-paced environment suited to initiative-taking individuals who can contribute to and successfully work in a multidisciplinary team.
Skills and experience:
* A MSc level qualification in molecular biology or equivalent.
* Practical experience in cloning DNA including: generating own strategies, creating theoretical sequence maps, primer design, PCR, bacterial transformation, and amplification.
* Strong experience with DNA purification techniques at varying scales, using kits and/ or self-packed hardware.
* Applicants should be well-versed in gel electrophoresis apparatus for DNA analysis and software for sequence analysis.
* Knowledge of running restriction digests, agarose gels and analyzing data.
* Experience in aseptic technique and controlled environments.
* Familiarity with industry quality standards such as ISO/ cGMP.
Touchlight is a successful scale-up business with a record of world-leading innovation and a welcoming, entrepreneurial culture.
We make Touchlight an extraordinary place to work by providing our employees with incredible facilities, flexible working and a competitive benefits and remuneration package.
We believe diversity drives innovation and for that reason we strongly encourage those from all backgrounds to apply for roles at Touchlight.
We are an equal opportunity employer and aim to build a workforce that is truly representative of the communities in which we operate and our customers.
If you need reasonable adjustments at any point in the application or interview process, please speak with the HR team who will be happy to support you.