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Sector: Science and Pharmaceutical, Technology
Contract Type: Permanent
Hours: Full Time
Site Name: UK - Hertfordshire - Stevenage
Posted Date: Mar 5 2025
We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
Please note this position is lab based.
For the newly founded NIVP team, we are looking for an Investigator who enjoys developing new in vitro models to create a positive impact on patients. NIVP is part of the Oncology Translational Research (OTR) team, and we aim to network closely with the other teams within and outside OTRO to contribute to preclinical and clinical development programs within GSK Oncology TA. The successful candidate will be part of a team that is being established in both Berlin and Stevenage. The core competence of the group is the establishment of new organoid models and their use in translational research, ranging from chemosensitivity testing to molecular manipulations for biomarker identification and target validation projects.
Key responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:
* Setting up cell culture protocols to grow and expand patient-derived organoids upon reception.
* Oversight and performing the cell culture/expansion.
* Performing patient-derived organoids quality control steps (cell density, proliferation rate and cytotoxicity evaluation).
* Collecting and reporting data to the lab head.
* Executing and delivering the project.
* Solving technical issues as part of a cross-functional project team.
Why you?
Basic Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
* BSc in Cell Biology/Oncology or related.
* Post doc experience or similar experience.
* Experience with non-cancer organoids or other complex cell culture models.
* A multidisciplinary mix of training/expertise in Molecular and Cell Biology.
* Significant experience in cell culture techniques (primary samples/patient-derived organoids), cytotoxicity analysis.
* Cellular and molecular Biology skills: cell isolation from human biopsies/samples; culture of normal and tumor cells from primary samples or immortalized cell lines; cell isolation from buffy coats; organoid establishment from fresh or frozen tissue; 3D culture in Matrigel or scaffolds (spheroids and organoids).
* Ability to communicate with team members from different backgrounds by training/discipline, as well as senior members of the GSK stakeholders/research partner units.
* Ability to deliver high quality, consistent results in a timely fashion with a positive can-do and result-oriented attitude.
Preferred Requirements:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
* MSc or PhD in Cell Biology/Molecular Biology or related.
* Background in cell biology.
* Experience in imaging.
* A track record of scientific publication.
* Experience in collaboration with biopharma.
Closing Date for Applications - Wednesday 12th of March (COB)
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
Why GSK?
Uniting science, technology, and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose - to unite science, technology, and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology, and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged, and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. #J-18808-Ljbffr