We are seeking to appoint an enthusiastic and highly motivated Research Assistant to join the Mitotic Progression group headed by Prof Ulrike Gruneberg. The Gruneberg lab studies the mechanisms safeguarding mammalian genome stability during cell division in the context of cancer. The post holder will focus on the mechanisms ensuring faithful chromosome segregation, with the goal of elucidating how kinases and phosphatases coordinate error correction and spindle checkpoint signalling during this process. The work will involve a combination of molecular biology and stable cell line generation as well as cutting edge fixed and live cell imaging. The post holder is expected to be able to manage their own academic research, possess excellent lab book keeping and communication skills and be able to present their results in research meetings. Applicants should hold a BSc/MSc degree in Biochemistry or Molecular Biology and have a demonstrable interest or experience in the cell cycle or chromosome biology field. You should be highly motivated, organised and reliable, and to be able to work independently as well as in a team. Previous experience with the genetic manipulation of mammalian cells and the generation of stable cell lines are essential criteria for the post. PhD in a relevant subject, some experience with immunofluorescence and live cell imaging analysis as well as recombinant protein production and mass spectrometry would be advantageous. This is a fixed-term appointment available for 1 year. If you are interested in this role, and have the skills and experience we are looking for, please apply online. You will be required to upload a CV and supporting statement as part of your online application. Informal inquiries about the position can be sent to Prof. Ulrike Gruneberg (ulrike.grunebergpath.ox.ac.uk). The closing date for applications is 12.00 midday on 10 January 2025. Interviews will be held as soon as possible thereafter.