Associate Scientist – Target Discovery | Biotech | CHO Cell Lines | CRISPR
Location: Oxford
Salary: £34k - £37k + benefits
We’re hiring an Associate Scientist to join an innovative biotech team focused on advancing mammalian cell line development. If you're experienced in CHO cell culture and CRISPR gene-editing, and you're passionate about target discovery, this could be your next move.
What you’ll be doing:
Designing and executing CHO cell culture experiments using small-scale and high-throughput models
Running CRISPR knockout screens and transfections for gene editing
Applying molecular and cell biology assays (qRT-PCR, Western blotting, ELISA)
Operating the BD FACSAria Fusion Flow Cytometer for single cell cloning and analysis
Supporting cell line development using technologies like Beacon and Ambr15
Writing SOPs, maintaining lab documentation, and training junior scientists
Ensuring lab safety standards and participating in out-of-hours cell culture as needed
What we’re looking for:
BSc/MSc with 3+ years or PhD with 1+ years in a biotech or pharma environment
Strong experience with CHO suspension cells, single-cell workflows, and genotyping
Skilled in CRISPR/Cas9 techniques and FACS-based cell sorting
Comfortable working independently and collaboratively in a fast-paced lab
Experienced in experimental planning, troubleshooting, and scientific communication
Nice to have:
Familiarity with Beacon, Ambr15, or 96-well high-throughput models
Experience working safely with lentiviral plasmid systems in a CAT2 environment
Understanding of monoclonal antibody production and critical quality attributes (CQA)
Looking to play a key role in breakthrough biologics research? Apply now