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Principal Scientist – Metabolism Bioscience Research, CVRM, Cambridgeshire
Location: Cambridgeshire, United Kingdom
Job Category:
Other
EU work permit required:
Yes
Job Reference:
23670ab628fc
Job Views:
8
Posted:
03.03.2025
Expiry Date:
17.04.2025
Job Description:
Are you an expert in in vitro pharmacology within the metabolic disease research area? Would you like to apply your expertise in a global company that is accelerating innovative science and turn ideas into life-changing medicines? Join us to discover future treatment of Cardiovascular, Renal and Metabolic (CVRM) diseases!
Working at AstraZeneca means being entrepreneurial, thinking big, and working together to make the impossible a reality. We are now recruiting a high calibre Principal Scientist to join the in vitro metabolism bioscience team within Research and Early Development CVRM. The position is placed at AstraZeneca’s Global HQ R&D site in Cambridge, UK.
CVRM is one of the three main therapeutic research areas within AstraZeneca which deliver candidate drugs into clinical development. The CVRM Metabolism Bioscience department has a dynamic environment that fosters collaboration and innovation. We are a team of professionals who are passionate about advancing science, to discover and develop novel therapeutics that will benefit patients suffering from diabetes, obesity, dyslipidaemia, and liver diseases.
What you’ll do:
This is a key scientific leadership position where the successful candidate can excel from both the lab bench and through project leadership. You will develop and lead scientific and technical capabilities required for progressing drug discovery projects within the metabolic disease area and influence the departmental strategy. You will lead the generation of key experimental data supporting multi-disciplinary project teams across Cambridge, Gothenburg, and Gaithersburg.
Role Profile:
* You will be an expert in the metabolic disease research area and will play an active role in the prosecution of a rapidly moving portfolio of drug projects.
* You will engage in developing the group's capabilities and projects through highly innovative scientific research aimed at bringing new treatment options to patients.
* You will work with the leadership team to contribute to the research strategy evolution and direction in the Metabolism Bioscience department.
* Act as a champion for novel approaches for drug discovery, promoting scientific debate and innovation within CVRM Research through inspiring personal leadership and mentorship.
* Recognised as an expert in your field; working on difficult drug projects to solve complex scientific questions and provide innovative solutions.
* You will play a leading role in the selection and validation of research targets through to early clinical development for a broad range of therapeutic modalities. Reporting to the Senior Director of Metabolism Bioscience, based in Cambridge, UK.
* You will be an expert in new in vitro models and methodologies with enthusiasm for laboratory work and scientific curiosity.
* You will act as bioscience lead and project leader on discovery projects to conduct, plan, and lead highly complex scientific projects with internal multidisciplinary teams and collaborators within and outside the organisation.
* Raise the scientific profile of CVRM both within AstraZeneca and externally through publications, presentations, and leading collaborations.
Essential for the role:
* PhD and postdoctoral experience in life sciences or equivalent relevant industry experience.
* 5+ years’ experience in the pharmaceutical/biotech industry and drug discovery.
* Expert scientific knowledge in metabolic disease research areas such as diabetes, obesity, dyslipidaemia, or MASH.
* Proven expertise in in vitro pharmacology, molecular and cellular biology with the ability to direct laboratory-based research.
* Evidence of scientific leadership recognised by publication record and enthusiasm to maintain a high external scientific profile through publication and conference presentations.
* Proven ability to manage complex projects, collaborations, and partnerships.
Desirable for the role:
* Experience of writing pharmacology sections of regulatory submissions.
* Significant experience of numerous in vitro and ex vivo technologies for assessing signalling endpoints for multiple target classes.
* Strong evidence of ability in leading several simultaneous projects/tasks.
* Extensive experience working with a network of research experts in the metabolism field.
So, what’s next?
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!
To be considered for this exciting opportunity, please complete the full application at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
Welcome with your application no later than 30th June.
Where can I find out more?
* Follow AstraZeneca on LinkedIn
* On Facebook
* Follow us on Instagram
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted: 10-Jun-2024
Closing Date: 30-Jun-2024
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