Department of Oncology, Old Road Campus Research Building, Headington, Oxford, OX3 7DQ About the Role An exciting opportunity has arisen for a Postdoctoral Researcher to join the Parkes lab, a vibrant and collaborative team dedicated to investigating the tumour microenvironment of chromosomally unstable cancers. Under the supervision of Professor Eileen Parkes, the successful candidate will be responsible for modelling and analysing the tumour microenvironment, with a particular focus on melanoma and oesophageal adenocarcinoma. You will also investigate cGAS-STING signalling, regulation at the endoplasmic reticulum, and T cell phenotypes and trafficking. A key aspect of the role includes bioinformatic analysis of RNAseq data and in vivo modelling of cancer.In addition to leading your own research, you will provide guidance and support to junior members of the lab, including PhD and project students, research assistants, and technicians. You will also contribute to the development of new research proposals and help shape future project directions. This full-time post initially fixed-term for 1 year, based at the Old Road Campus Research Building, Oxford. About You You will hold a relevant DPhil/PhD or be within three months of submission, along with proven experience in tumour microenvironment or immunology. You should have a Home Office Personal Licence and hands-on experience with tumour models.You will bring expertise in chromosomal instability, the cGAS-STING pathway, and T cell biology, with a track record of publications and conference presentations at national and international levels.Technical proficiency should include CRISPR-Cas9 gene editing, cell and co-culture systems, molecular biology techniques, multispectral flow cytometry, and bioinformatic analysis of transcriptomic (RNAseq) datasets. Experience with image analysis, particularly for immunofluorescence, is desirable. You should be confident managing your own academic research, generating ideas for new research directions, and contributing to the preparation of funding applications. Strong communication skills, a collaborative mindset, and the ability to provide mentorship to junior colleagues are essential. Application Process Applications for this position must be submitted online .