The DOU is a fully integrated "Biotech style" drug discovery organisation with cutting edge facilities ( We are passionate about tackling unmet medical need. We have two areas of activity: drug discovery for globally important neglected and emerging infectious diseases (including TB, malaria, coronaviruses), that affect millions of people across the world every year and Innovative Targets across a variety of different diseases.
We work to BioPharma philosophy and standards, incorporating a dynamic, goal driven project management strategy based on Target Product Profiles and Compound Selection Criteria. Our team of 130 scientists, has extensive experience of all aspects of drug discovery gained within the BioPharma industry. Our exceptional skill set within a university enables us to work with major BioPharma and technology companies and world-class Life Sciences research partners, to improve how high-quality drug discovery is carried out for these diseases.
We are recruiting for a highly motivated Computational Chemist to join our Computational Drug Discovery department. The salary will be commensurate with experience. The role is embedded in the computational chemistry applications team and you will contribute to the DOU drug discovery effort by working collaboratively with medicinal chemists, DMPK scientists, structural biologists, biologists and biophysicists. It provides an opportunity to:
* be a part of a world-leading university-based drug discovery group
* develop cutting edge computational approaches and directly apply them to drug discovery
* contribute to delivering drug candidates that address unmet major global diseases.
Please note that the decision about the successful candidate's grade will be made at the appointment stage based on the candidate's knowledge and experience.
Please note that applications made on a part time basis will be considered.
Your priorities will include:
The successful candidate will report to the head of the CompChem Applications team and is expected to impact the DOU project portfolio using a variety of computational chemistry and data science approaches. In particular:
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o Collaborate within interdisciplinary Discovery teams (internally and with external collaborators) to deliver on project strategy, and drive project execution
o Use timely decision making to ensure focus and delivery of key project objectives. Promote high levels of productivity and urgency
o Help build a reputation for innovation and excellence in computational drug discovery in collaboration with other DOU scientists.
Who we're looking for:
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o Highly motivated, self-directed individuals qualified with a PhD in Computational Chemistry, Cheminformatics, Computational Medicinal Chemistry or related subjects
o Experienced in the application of Computational Chemistry for Drug Discovery projects
o Excellent knowledge of commercial and OS modelling software. Good python programming language, Linux OS experience
o Strong interpersonal, communication and coordination skills
o The ability to report, organize and publish research data suitable for external publication
o Strong solution-oriented attitude, a spirit of innovation and a high motivation to learn