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Senior Lecturer and Janet Owens Parkinson's UK Senior Research Fellow at Newcastle University
Overview
This PhD will be the first prospective study to investigate delirium in inpatients with Lewy body disease (LBD) using electroencephalograms (EEG). You will determine the feasibility of collecting EEG in LBD inpatients with delirium, evaluate its use as a potential biomarker and explore its potential mechanisms in LBD.
Delirium is a distressing acute neuropsychiatric syndrome associated with an increased risk of developing dementia. We have shown that delirium is common in LBD inpatients (66%), but delirium is often missed in LBD due to overlapping symptoms, and the underlying mechanisms are unclear. Abnormal EEG scans, a widely available, non-invasive clinical test, may be a useful biomarker of delirium.
This novel translational project includes collecting mobile-EEG data in inpatients with LBD. You will be supported and trained to complete delirium assessments, collect clinical data and mobile-EEG scans with participants in hospital. You will learn to apply advanced EEG analytic approaches to compare EEG data on participants with delirium and after recovery. This will enable precision monitoring and timely diagnoses of delirium in LBD.
You will benefit from cross-disciplinary expert training in the fields of psychology, clinical care, neurophysiology and advanced analytic approaches in people with LBD and delirium. You will be integrated within a Brain and Movement Newcastle University providing a supportive environment with researchers spanning all career levels from both Newcastle and Exeter. In addition, you will benefit from support from the Alzheimer’s Society LBD Doctoral Training Network and visits to Exeter, as well as support and training in scientific communication, patient and public involvement and engagement and conference travel.
Number of awards: 1
Award duration: Four years
Sponsor: Doctoral Training Centre for Lewy body dementia | Alzheimer's Society
* Dr Rachael Lawson, Newcastle University Staff Profile | Faculty of Medical Sciences | Newcastle University
* Professor Louise Allan, University of Exeter Louise Allan Profile | University of Exeter
* Professor Mark Baker, Newcastle University Staff Profile | Faculty of Medical Sciences | Newcastle University
Eligibility Criteria
You must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in a subject relating to biomedical sciences, including psychology, neuroscience, medicine or bioinformatics. Further qualification such as an MRes is advantageous. Successful international candidates will be required to fund the difference between the home fees and international fees.
How To Apply
You must apply through the University’s Sign in· Newcastle University Admissions Portal. In ‘Course choice’ tab, put ‘Postgraduate Research’ in ‘Type of Study’, ‘Full Time’ in ‘Mode of Study’, ‘2025’ in ‘Year of Entry’, code ‘8440F’ in ‘Course Title’, blank in ‘Research Area’. Press ‘Search’, select ‘PhD Translational and Clinical Research (FT)’, and save selection.
Either upload a document or write into ‘Personal Statement’. Put code ‘TC106’ in ‘Studentship/Partnership Reference’. When prompted for research proposal, select ‘Write Proposal’ and type in the title of the research project from this advert. A research proposal is not required. You can also upload a covering letter and CV, please state how your interests and experience relate to the project.
You must submit one application per studentship, you cannot apply for multiple studentships on one application.
Dr Rachael Lawson
Telephone: +44 (0) 191 208 1277
Seniority level
* Internship
Employment type
* Full-time
Job function
* Education and Training
* Industries: Higher Education
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