Quotient Sciences is a drug development and manufacturing accelerator providing integrated programs and tailored services across the entire development pathway. Cutting through silos across a range of drug development capabilities, we help biotech and pharma customers save precious time and money in getting drugs to patients.
We employ more than 1,100 talented individuals globally, located at state-of-the-art development, manufacturing and clinical facilities in the UK and USA. Science, Agility and Culture are the core components that define Quotient Sciences, enabling us to do what we do in the way that we do it.
People join Quotient Sciences because we are a respected member of the drug development community that’s focused on innovation and are driven by an unswerving belief that ideas need to become solutions, and molecules need to become cures, fast. Because humanity needs solutions, fast.
Summary of job purpose
* To lead pre-clinical or stand-alone formulation programmes requiring specialist formulation knowledge including the preparation of associated protocols and reports.
* To design and conduct formulation development work including pre-formulation and formulation characterisation.
* To design the development and validation of radiolabelling methods for clinical studies.
* To support the transfer of formulation and radiolabelling methods into GMP clinical manufacturing, with input on manufacturing protocols, validation criteria and other key parameters.
* To write experimental protocol and reports.
Main tasks and responsibilities
* Lead pre-clinical formulation development programmes.
* To plan experiments and write protocols, according to an agreed work schedule.
* To prepare and characterise formulations.
* To perform radiolabelling method development and validation activities.
* Train new / existing staff as required.
* Work in a safe responsible manner at all times to GMP.
* Storage, use and disposal of Radioactive Isotopes in line with regulatory requirements and PP SOPs, to include liaising with Radiation Protection Supervisor (RPS) or nominated Deputy on any radiation protection issues that may arise.
* Keeping detailed and accurate records of all work undertaken.
* Accurate analysis and calculation of results, in line with written Protocol and/or SOPs of the company.
* To communicate progress of in vitro and in vivo projects effectively to senior managers or Quotient staff as required.
* To be aware of the need for confidentiality outside the company.
* To perform other duties as reasonably required.
Additional Tasks/responsibilities
* To source and control formulation excipients.
* Provide formulation expertise to support other formulation scientists within the group.
Qualifications and experience required for competent performance
* Minimum degree level qualification in pharmacy or chemistry related discipline.
* >5 years’ experience in formulation development.
* cGMP experience will be an advantage.
Job Demands
The job may involve the following:
* Very high concentration of work.
* Strict and tight deadlines.
* Having to juggle a range of tasks/issues simultaneously.
* Working in a hazardous environment with high requirement to follow safety procedures.
* Working outside normal working hours.
* Needing to respond to client demands.
This Job Description is designed to summarise responsibilities, assist in benchmarking performance, and provide information for job applicants. It is by no means exhaustive and is not intended to restrict a job holder’s development or level of performance.
Application Requirements
When applying for a position with Quotient Sciences to be able to work in our organisation you must be aged 18 years or over and not have been debarred by the FDA. If you indicate you are under the age of 18 or have been debarred then your application will be automatically declined.
Our Commitment to Diversity, Equity and Inclusion
Quotient Sciences are advocates for positive change and conscious inclusion. We strive to create a diverse Quotient workforce and develop a workplace culture that provides a sense of acceptance for every person within our organisation. As a global employer, we recognise the value in having an organisation that is a true reflection and representation of our society today.
Specifically we will not discriminate on the basis of race, colour, creed, religion, gender, gender identity, pregnancy, marital status, partnership status, domestic violence victim status, sexual orientation, age, national origin, alienage or citizenship status, veteran or military status, disability, medical condition, genetic information, caregiver status, unemployment status or any other characteristic prohibited by federal, state and/or local laws.
This applies to all aspects of employment, including hiring, promotion, demotion, compensation, training, working conditions, transfer, job assignments, benefits, layoff, and termination.
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