Applications are invited for a Research Technician position in the group of Dr Richard Tyser within the Wellcome ¿ MRC Cambridge Stem Cell Institute (CSCI) based at the Cambridge Biomedical Campus. The Wellcome - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments ( https://www.stemcells.cam.ac.uk/ ). The Tyser Lab studies how the mammalian heart forms during embryonic development, exploring how the initiation of function occurs and to what extent this defines and influences the progression of subsequent cardiac morphogenesis. We use a combination of different models including primary mouse and human samples as well as in vitro human Pluripotent Stem Cell differentiation (Tyser, Ibarra-Soria et al. Science 2021; Tyser, Mahammadov et al. Nature 20201; Tyser, Miranda et al. Elife 2016). This research will answer questions of fundamental biological importance with clear clinical relevance such as providing new insight into the origins of Congenital Heart Defects (CHD) as well as augmenting cell-based approaches to treat disease. We are seeking an enthusiastic and dedicated Research Technician to join our research group with significant experience working with mice and of laboratory-based biological research. The successful candidate will support the research team by providing technical assistance, such as aiding in the management of genetic mouse models and sample generation. As such, the candidate should have good interpersonal and organisational skills, paying close attention to detail. Other responsibilities include a range of tasks to ensure the smooth running of the laboratory, such as ordering and maintaining laboratory supplies, maintaining and updating reagent databases. An understanding of the principles of cellular and molecular biology (DNA & RNA extraction, quantitative PCR, molecular cloning) is essential. It is essential that the successful candidate can work both independently and as part of a research team. For this position we would welcome applications for part-time/flexible working patterns, including shorter working days. Fixed-term: The funds for this post are available until 29 June 2029 in the first instance. Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check, a health assessment and a security check. Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online Application form. Please include details of your referees, including email address and phone number, one of which must be your most recent line manager. The closing date for applications is: 13th Febuary 2025 The interview date for the role is: To be confirmed Please quote reference PS44902 on your application and in any correspondence about this vacancy. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Further information Further Particulars Apply online