Site Name: UK - West Sussex - Worthing
Posted Date: Feb 12 2025
Downstream and Scale-up Manager
Closing Date for Applications – 26th February (COB)
This is a site-based role at Worthing, within the Global Manufacturing Science & Technology (MSAT) organisation.
The Global Manufacturing Science and Technology (MSAT) organisation provides strategic direction and technical and operational support to ensure that GSK Global Supply Chain network, site goals and objectives are achieved through focused strategy execution.
MSAT is the keeper of the body of knowledge associated with the formulation, device components, analytical testing and manufacturing unit operations, creating the instruction set and ensuring manufacturing operations stay aligned with the registered process. The primary objective is to ensure manufacturing processes are capable, compliant, in control, continuously improved and aligned across Sites.
MSAT’s primary functions are to lead technology transfers, implement control strategies, provide technical process support, and implement new products and new modalities for commercial products and product-related improvement programs within the GSK GSC perimeter.
In this role you will be responsible for leading a team of scientists and engineers to develop new or second generation fermentation, cell culture and downstream extraction and purification processes for small and large molecule APIs, intermediates and enzymes, with transformative impact including to sustainability. You will be accountable for the team’s delivery of screening, optimisation, characterisation, validation, scale-up and tech transfer of processes to partners in GSC, R&D, Vaccines or external supply.
In this role you will:
* Provide professional and scientific leadership to enable fermentation scientists and downstream engineers to deliver on programme objectives to develop, characterize and/or validate processes across multiple scales and platform technologies.
* Promote and monitor technical standards. Identify and champion alternative strategies, ideas and opportunities. Make effective decisions based on interpretation of results across multiple programs.
* Manage team resource and expertise allocation across projects with the ability to prioritise new opportunities.
* Work collaboratively as a key member of the department leadership team.
* Maintain a high level of relevant scientific expertise and visibility; and provide scientific leadership in areas of fermentation, cell culture, extraction and purification.
* Define and drive the highest levels of safety and good lab practice across the department.
Why you?
Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
* Graduate qualification in Chemical or Biochemical Engineering, Biochemistry or equivalent life sciences.
* Strong scientific, supervisory and leadership skills.
* Strong interpersonal and leadership skills. Solid team player able to function within team-based organisation.
* Able to prioritise and decide appropriate course of actions. Effective at implementing decisions.
* Knowledge of cGMP and regulatory requirements.
Preferred Qualifications & Skills:
If you have the following characteristics, it would be a plus:
* Previous experience in the pharmaceutical industry and/or process development including supervisory or management experience.
About Worthing Manufacturing Site:
Manufacturing at the Worthing site is for antibiotics. It is advised that you take this into consideration when deciding to apply for this position.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.*(*US only).
#J-18808-Ljbffr