Senior Scientist (and up) - Purification Scale Up
Title: Senior (and up) Purification Process Scientist (Prep-HPLC)
Location: Cambridge
Employment Type: Permanent
Salary: DOE - Including Annual Bonus
We are currently working with a global leader in the pharmaceutical industry who is investing in their Small Molecule Purification department with an exciting new avenue in peptide/Oligonucleotide research.
Due to their pursuit of this area of research, they are looking to take on an experienced Purification Process Chemist with Preparatory HPLC and/or Preparatory SFC (Supercritical Fluid Chromatography) scale-up experience. This is an amazing opportunity to develop your career and be the pivotal cornerstone to this team’s success.
The successful candidate will support the purification development for some of the company's chiral protein R&D projects and work closely as part of a multi-disciplinary team with R&D and Process Development scientists. This will not be a routine purification role. You will need to have experience scaling up purification processes, and purification tech transfer, developing and utilizing automation for high throughput purification. This is essential.
The main duties and responsibilities will include:
* Development and optimisation of small molecule purification using Prep HPLC and Prep SFC.
* Process development and scale up of purification methods to KG scale.
* Develop automated processes to aid in scale up.
* Tech transfer of in-house processes to international sites.
* Collaborating closely with a range of internal stakeholders to help define project milestones and deliverables.
* Compiling clear and concise reports summarising your work.
Required Experience:
* A higher education qualification in analytical chemistry, chemistry, or biochemistry.
* Experience in purification (Prep HPLC or SFC) process development with Small molecules (Essential, Oligonucleotides beneficial).
* Experience with purification process tech transfer (Essential)
* Experience with automating processes (Essential)
* Experience leading and managing your own projects.
* Experience with Oligonucleotides is highly desired.
If you are interested in this role and require more information, please contact Selby De Klerk on 07825683514 or drop me a message with your CV.
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