About the Role
We are seeking a Postdoctoral Scientist to join the Translational Gastroenterology Unit, Experimental Medicine, Nuffield Department of Clinical Medicine (NDM). This post is to work on the study of T cell responses to CMV in the mouse. We aim to define their role in healthy tissue, in responses to vaccines, and in response to infectious challenges/vaccines and cancer. We also aim to understand the role of MAIT cells in supporting CMV-specific “inflationary” T cells.
The postholder will need to perform detailed analyses of CMV-specific T cells and MAIT cells in in vivo models and, where relevant, in human samples. Experience of mouse immunology studies and studies of T cell functions is essential. Experience in studies of antiviral T cell responses and/or T cell responses to tumors is a key asset, and experience with studies of unconventional cells is additionally an advantage. This post has a strong bioinformatic focus, so the ability to apply single-cell RNAseq methods to antiviral, anti-tumor, and MAIT cell biology is essential.
You will hold a PhD in Immunology or another closely allied area. Prior work in the area of immunology, including studies of T cell phenotype and function in in vivo models, is essential. It is desirable to have experience of actively collaborating in the development of research articles for publication.
The post is full-time (pro rata for part-time) and fixed-term for 2 years.
What We Offer
* Flexible working
* An excellent contributory pension scheme
* 38 days’ annual leave (including bank holidays)
* A comprehensive range of childcare services
* Family leave schemes
* Cycle loan scheme
* Discounted bus travel and Season Ticket travel loans
Application Process
Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Thursday 20th March 2025 will be considered.
£38,674 to £46,913 per annum
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