About the Company A global specialty pharmaceutical group focused on developing and commercializing treatments for patients with genetic, metabolic, systemic, and life-threatening acute disorders, as well as healthcare solutions for the general population. About the Role The Senior Data Manager will oversee data management activities for interventional and non-interventional clinical studies, ensuring compliance with applicable regulations, ICH/GCP guidelines, Standard Operating Procedures (SOPs), and study plans across assigned clinical programs. This role is crucial in managing end-to-end data management activities from study initiation to closeout, maintaining a focus on data integrity, validity, and reliability to support study delivery according to strategic timelines and budgets. Responsibilities Based in Egham, the Senior Data Manager is expected to: Clinical Study Delivery Support the Director of Global Clinical Affairs in implementing a vision for Clinical Affairs that enhances the quality, cost, speed, and efficiency of clinical study delivery. Maintain oversight of data management status and proactively communicate progress, risks, issues, or changes that may affect quality, timelines, or budget to the Clinical Study Lead. Collaborate cross-functionally to ensure transparency, knowledge transfer, and alignment within studies. Focus areas include: Assisting in implementing Quality by Design principles during protocol development. Managing start-up activities, including reviewing and developing study documentation (e.g., Statistical Analysis Plan, Data Management Plan), designing Case Report Forms, and conducting database selection, building, and testing. Overseeing study monitoring and implementing risk-based quality management processes to ensure data quality, integrity, and participant safety. Managing database lock and transfer processes and supporting the delivery of tables, figures, and listings. Ensuring study files accurately reflect data management activities and that documents are filed contemporaneously. Supporting selection and oversight of service providers, monitoring budgets, and managing performance. Ensure inspection readiness for studies and support GCP audits and inspections. Enabling Activities Engage in initiatives that enhance the efficiency of programs and studies, including process improvements, digital integration, and knowledge transfer. People Management Provide leadership, support, feedback, coaching, and mentoring to members of the Clinical Affairs team. May supervise direct reports within the Data Science team, as agreed with the Clinical Program Lead and Director of Global Clinical Affairs. Assist in training relevant staff as necessary. Other Responsibilities Support the development of external communications related to clinical studies. Attend conferences and external events. Conduct internal training sessions when required. Essential Requirements Bachelor's degree or equivalent experience in Mathematics, Science, or a related field. Proven experience in the pharmaceutical or biotech industry, specifically in Clinical Research and/or Clinical Data Management. Strong knowledge of international clinical research regulations and ICH/GCP requirements. Experience with clinical trial databases, data flow management, and eCRF design. Excellent written and verbal communication skills. Strong project management abilities. Independence and the ability to lead a team effectively. Observational and analytical skills. Good time management skills with the ability to meet tight deadlines. Ability to quickly problem-solve and make decisions. What’s on Offer Competitive salary with benefits. An opportunity to contribute to work that directly benefits healthcare and improves lives. Hands-on experience with high commercial exposure. Collaboration with world-leading scientific experts. A chance to work with dedicated colleagues in a fast-growing company focused on cutting-edge science and commercial success.