From £54,621 with benefits, subject to skills and experience
Job Title: Computational Chemist
Reports to: Yew Mun Yip
Closing Date: 16/Mar/2025 23.59 GMT
Salary for this Role: From £54,621 with benefits, subject to skills and experience
Job Description:
SLRS Computational Chemist
Details of the role:
This is a full-time, permanent position on Crick terms and conditions of employment.
About us…
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture.
About the role…
We are looking to hire a Computational Chemist to join the Chemical Biology Science Technology Platform at the Crick.
If you have a PhD in Computational Chemistry, Cheminformatics, or a related field and experience in applying computational chemistry to chemical biology or medicinal chemistry research, this may be the perfect role for you.
You will be joining a multidisciplinary team, working alongside another computational chemist on data analysis and in silico predictions, using computational methods to refine experimental design. Some of the key responsibilities of this role will be applying computational techniques to small molecule discovery, including virtual screening and molecular dynamics simulations, as well as maintaining cheminformatics systems, which is why knowledge of programming such as Python is essential.
Collaboration is also a key aspect of this role, and the successful candidate will work closely with STP chemists and researchers across the Crick to integrate computational techniques into the development of chemical probes and small molecules.
What you will be doing…
* Develop and Maintain Cheminformatics Resources: Design, establish, and manage cheminformatics tools that support the STP’s projects.
* Project Support: Provide computational chemistry support across STP projects, applying virtual screening, compound library design, structure-based drug design, and other computational methods to address project goals.
* Collaborative Problem-Solving: Work closely with multidisciplinary teams within the STP and across the Crick to design and implement computational solutions for complex research questions in chemical biology.
* Continuous Development and Knowledge Sharing: Stay updated on advancements in computational chemistry, applying relevant methods to STP projects.
About you…
Essential skills:
* PhD in Computational Chemistry, Cheminformatics, or a related field.
* Proven experience in applying computational chemistry to chemical biology or medicinal chemistry research in academic or industrial settings.
* Strong programming skills (e.g., Python, Bash) and familiarity with cheminformatics and molecular modelling tools (e.g., RDKit, Flare, AMBER, GROMACS).
* Demonstrated ability to collaborate and communicate effectively within multidisciplinary teams.
* Excellent problem-solving and organizational skills with the ability to manage multiple projects simultaneously.
What will you receive?
* Visas: Applicants for this role will be eligible for sponsorship to work in the UK.
* Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
* Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
* Health & Well-being: 24/7 GP consultation services, occupational health services, and mental health support programs.
* Work-Life Balance: Back-up care for dependents and childcare support allowance.
* Perks: Discounted gym memberships and subsidised on-site restaurant.
* Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.
Equality, Diversity & Inclusion: We welcome applications from all backgrounds and are committed to providing equal employment opportunities.
The Francis Crick Institute is a biomedical discovery institute researching the biology underlying human health.
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