We have created a new role for an experienced statistician to act as a strategic partner for project teams in providing statistical expertise for the design, conduct, delivery, and reporting of CDD-sponsored clinical trials. You will be joining at a pivotal moment in the evolution of the CDD and this role offers an opportunity to play a key role in shaping the design of early phase clinical trials investigating a broad range of next generation therapeutics.
Key Responsibilities:
1. To secure statistical expertise for study design, protocol development, and delivery of CDD-sponsored clinical trials.
2. Ensure a consistent approach is taken across the CDD trial portfolio by acting as the primary point of contact for project teams with external statisticians.
3. Preparation of requests for proposals for statistical support from external vendors/consultants and lead on review and selection.
4. Where appropriate, fulfil the role of trial statistician for CDD-sponsored clinical studies.
5. Liaise with relevant functions to support the operational delivery of clinical studies including development of statistical analysis plans and electronic case report forms.
6. Provision of statistical input into the preparation of clinical study reports and trial publications.
7. Review and QC of agreed deliverables from biostatistics vendors/collaborators (e.g. statistical analysis plans, protocol sections, reports).
8. Communicate and ensure compliance of vendors and other relevant third parties with CDD SOPs and working practices.
9. To demonstrate a commitment to the importance of increasing equality, diversity, and inclusion in CRUK's drug development and clinical trial portfolio.
Minimum Requirements:
1. Extensive experience of working as a trial statistician for early phase oncology studies, including first-in-human trials.
2. Comprehensive knowledge of statistical methodology including frequentist and Bayesian methods.
3. Excellent understanding of oncology drug development including current and emerging treatment paradigms and incorporation of clinical and translational endpoints.
4. Fluency in statistical programming language e.g. R or Stata.
Desirable:
1. Experience of working in the pharma or biotech sector.
2. PhD in Statistical Science.
3. Late phase development experience.
Please note: Cancer Research UK can consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application. Our vision is to create a charity where everyone feels like they belong, benefits from and participates in the work we do. We actively encourage applications from people of all backgrounds and cultures, particularly those from ethnic minority backgrounds who are currently under-represented. We want to see every candidate performing at their best throughout the job application process, interview process, and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact recruitment@cancer.org.uk or 020 3469 8400 as soon as possible. Unfortunately, we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.
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