A GMP scientist position is available within the Centre for Cell, Gene & Tissue Therapeutics. The post holder will be responsible for supporting a new, GMP-compliant lentiviral manufacturing facility in brand new, purpose-built clean rooms and assisting the development and implementation of novel intermediate scale lentiviral manufacturing techniques in suspension cell bioreactors.
The Post Holder will be responsible for supporting the process development team transfer the process to GMP.
The post holder will also help to develop new downstream purification and packaging systems.
Main duties of the job
What you'll do:
* Develop and implement cutting-edge lentiviral production techniques using state-of-the-art production equipment.
* Play a key role in building and qualifying a GMP process from the ground up.
* Conduct and develop analytical assays for viral vectors, including flow cytometry, sterility testing, and qPCR.
* Analyse and interpret complex batch data, contributing to process optimisation.
* Maintain lab equipment and contribute to a compliant and efficient lab environment.
Person Specification
Experience
Essential
* Research experience in viral vectors
* Cell culture experience
* Analytical assays experience
Desirable
* GMP experience
* Viral vector manufacture and scale up
* Bioreactor experience
Education
Essential
* BSc or higher in relevant field
Desirable
* MSc or higher
Employer details
Employer name
Royal Free London NHS Foundation Trust
Address
Royal Free Hospital
Pond Street
London
NW3 2QG
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