We are looking for several highly motivated Clinical Bioinformaticians to join our expanding Bioinformatics team at the South East Genomic Laboratory Hub (SEGLH). The posts will be based at either Guy's Hospital or King's College Hospital, but with a planned consolidation to a hub at Blackfriars.
The posts will be part of the team supporting the clinical diagnostics services of both Guy's and King's College Hospitals, covering several rare disease and cancer diagnostic laboratories. You would have the opportunity to develop and troubleshoot both somatic and germline pipelines, develop and manage applications supporting the diagnostic process and manage large datasets for reporting.
The successful applicant will be dedicated and enthusiastic with knowledge and experience of working with NGS pipelines and large datasets, as well as possessing strong programming and troubleshooting experience. Applicants should be good communicators, be able to take initiative, support continual quality improvement and prioritise workload. The role requires consistent attention to detail and excellent organisational skills.
Applicants will be expected to have attained or be working towards HCPC registration. STP trainees in their final year of training, or applicants with relevant MSc or PhD and bioinformatics experience, who are interested in transitioning to a clinical setting, are also encouraged to apply.
Main duties of the job
This is an exciting opportunity to join a dynamic team which is highly valued in Synnovis Genomics. The successful candidate will support existing diagnostic services in the South East and also be involved in a very active programme of assay and technology development.
The role would involve maintaining and operating the bioinformatics pipelines for the processing of next generation sequencing data for both Guys and King's College Hospitals, managing multiple pipelines supporting services for the Genomic Medicine Service.
The post-holders will work with other clinical scientists to support the development, validation and implementation of new/updated diagnostic tests. This will include developing and delivering validated and accredited software for delivery of diagnostic services following clinical best practice guidelines, as well as working with cloud-based infrastructure, local databases and the latest technologies to deliver bioinformatics services.
We support a flexible, hybrid working pattern. The posts will be based at Guy's Hospital or Kings College hospital, though occasional travel to other Synnovis sites, such as other trust sites may be requested.
Job responsibilities
At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites.
Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.
Person Specification
Qualifications
* HCPC Registration (or working towards registration)
* BSc in bioinformatics, biological sciences or related field
* PhD in bioinformatics, biological sciences or related field
Experience
* Experience of analysing next generation sequence data
* Experience of developing, implementing and maintaining bioinformatic data analysis pipelines
* Developing cloud-based genomics apps, e.g. on AWS and DNAnexus
* Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)
Skills & Knowledge
* Ability to use scripting languages such as Python, Java and Bash
* Ability to trouble shoot and independently solve problems
* Demonstrable broad level understanding of molecular biology and human genetics.
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Guy’s Hospital or Kings College Hospital
Depending on experience £54,320 to £60,981 per annum depending on experience
Contract
Permanent
Working pattern
Full-time
Reference number
J206-VIS6202
Job locations
Guy’s Hospital or Kings College Hospital
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