Job responsibilities The main duties and responsibilities of a Nurse Practitioner include: Carrying out clinical examination of patients in their care Performing diagnosis based on their assessment of the patient Taking specimen urine etc) samples and ordering test samples Creating short or long-term treatment plans Managing and providing post-surgical care to patients Offering special instructions to patients such as nutritional advice, information about weight management, etc. Performing routine medical procedures Performing periodic evaluations of their patients and referring them to specialists as necessary