We are a world-class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in the economic, social, and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.
The Role
We are recruiting a motivated and curiosity-driven Research Assistant to join an exciting new Medical Research Council funded project concerning Trypanosoma brucei parasites.
The project is focused on uncovering the molecular mechanisms by which trypanosome parasites proliferate and transmit between hosts using multidisciplinary approaches. Trypanosomes are the cause of three Neglected Tropical Diseases (Sleeping Sickness, Leishmaniasis, and Chagas disease) in humans and are spread by insect vectors. In the research group, we culture African trypanosome parasites in vitro and use CRISPR/cas9 technology to genetically modify the parasites, rapidly generating mutants and fluorescent parasite lines for study. We use methods including proteomics, microscopy, flow cytometry, and single-cell transcriptomics.
You will have a key role in delivering a high-throughput genetic modification screen using parasite culture and genetic manipulation, robotics, fluorescence microscopy, and flow cytometry. To do this, you will use the state-of-the-art Bioscreening, Bioimaging, and Flow Cytometry units all housed within the institute. In addition to joining the multidisciplinary Biosciences Institute, you will also interact with the global community of parasitology researchers.
In this role, you will learn modern molecular lab-based and bioinformatic techniques, gain experience of eukaryotic cell culture and genetic modification, and develop expertise in parasitology. Note there is also potential to complete a PhD in conjunction with this post.
This post is fixed-term until 31 March 2028.
For informal enquiries contact: emma.briggs@newcastle.ac.uk.
To apply for the position, we’ll need a copy of your CV which should outline how you are suitable for the role, with a particular focus on the essential criteria in the knowledge, skills, and experience as listed in the job description (available on the university's website, accessed by the 'Apply' button).
£32,296 to £33,882 per annum.
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