A Postdoctoral Researcher position is available to join the Schlimpert Group at the John Innes Centre, working on cutting-edge science in the field of Molecular Microbiology.
About the John Innes Centre
The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet, sets out our ambitious long-term goals for the game-changing impact of our science globally.
The successful applicant will be based in the Laboratory of Dr Susan Schlimpert. Research in the Schlimpert group focuses on understanding the molecular mechanisms that underpin cellular development and morphogenesis in actinobacteria. The group’s current research has several sub-objectives:
1. Cell division in Streptomyces and Mycobacteria
2. Regulation of bacterial multicellular development
3. Functional diversity of NLRs in Streptomyces
The team maintains a vibrant and stimulating research atmosphere – currently consisting of two postdoctoral scientists with an additional postdoc joining in spring 2025, and two postgraduate students. We also regularly host projects for undergraduate students.
The role
We are looking for one Postdoc to work on a new ERC Consolidator Grant project BacNLR, which aims to unravel the functional diversity of NLR-like proteins in bacteria. The role is initially for three years with the potential to extend to up to five years.
The postholder will combine molecular microbiology, protein biochemistry, fluorescence microscopy, and metabolomics to demonstrate the role of NLR-like proteins in regulating antibiotic production and/or bacterial multicellular development and immunity in Streptomyces. We also aim to elucidate the structural basis of NLR protein complexes and their binding partners using cryo-electron microscopy.
This project will uncover new roles of NLR signalling pathways and provide an innovative experimental strategy to boost the production of medically important molecules.
The ideal candidate
The successful candidate will have a PhD in Microbiology, Biochemistry, or a related discipline and should ideally meet the following criteria:
* Proven ability to work with bacteria and skilled in molecular biology techniques
* High level of interest in understanding the molecular basis of NLR signalling in bacteria and its potential impact on the biology of Streptomyces
* Experience in protein biochemistry, fluorescence microscopy and/or metabolomics and/or structural biology
* Committed to research excellence with a demonstrated relevant publication track record in leading scientific journals
* A proven ability to conduct independent research, as well as to work effectively as a member of a research team
* Interest in mentoring and supervision of visitors and students
Additional information
As part of your application, candidates will need to submit their CV along with a brief but strong cover letter that describes your career narrative to date, how this relates to the advertised position and how this position fits with your career plans, and a publication list.
For further information and details of how to apply, please visit our website here or contact the Human Resources team on 01603 450814 or nbi.recruitment@nbi.ac.uk quoting reference 1004789. This role meets the criteria for a visa application, and we encourage all qualified candidates to apply.
We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family-friendly workplace. The Institute is also a member of Stonewall’s Diversity Champions programme.
The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.
Salary: £36,720 - £44,500 per annum depending on qualifications and experience.
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