Senior Scientist - Biomarkers
We are seeking a motivated Bioanalyst to join our group based at our flagship R&D site in Stevenage, Hertfordshire. The team supports soluble biomarker measurements for clinical studies using a variety of ligand binding assay techniques. The data we generate is critical to helping GSK Project Teams make decisions on progressing new molecules towards becoming medicines.
In this role you will develop and validate bespoke immunoassays for soluble biomarker endpoints in support of clinical studies. You will be responsible for the delivery of high-quality assay data to study teams for early-stage clinical studies (e.g. enabling and FTiH). You will also work with our CRO partners, ensuring that assay transfers proceed smoothly prior to later stage clinical studies.
This role is an on-site position and the successful applicant will be based at GSK’s Stevenage R&D site.
We are looking for a team member who is keen to further their career in soluble biomarker immunoassay analysis alongside complimentary automation techniques in a regulatory setting.
We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
In this role you will:
* Build effective relationships with the various supported groups within and outside the department.
* Hold yourself accountable for delivering high quality biomarker results, managing timelines whilst being fully compliant with GCP regulatory requirements.
* Adopt a technology agnostic attitude and openness to analytical techniques when planning support for all modalities.
* Work as part of the team to ensure day-to-day laboratory responsibilities are met (reviewing study plans/reports etc).
* Drive the departments “automation first” objective for both the laboratory work and the pre-analytical and post-analytical workflows.
* Partner with external companies, institutes and consortium to deliver solutions.
* Drive innovation and actively contribute to process improvements (scientific, regulatory/quality).
Basic Qualifications & Skills:
* Graduate degree in biology, biochemistry or pharmacology.
* Experience running Bioanalytical or Biomarker studies in a GxP regulated environment with a focus on good record keeping and data integrity.
* Experience in tailoring bespoke biomarker assay validations to the context of use for the data.
* Experience in the method development and validation of quantitative immunoassays using one or more of the following Gyrolab, MSD, Simoa, SMCxPRO (or Erenna).
* Ability to effectively manage multiple priorities, communicate recommendations clearly and enjoy working within a team.
* Ability to present both written and oral communications to R&D stakeholders.
Preferred Qualifications & Skills:
* Understanding of regulatory aspects of human biological sample management, Good Clinical Practice (GCP).
* Experience of interacting with LabQA/regulatory inspectors.
* Experience with automated liquid handling platforms (e.g. Labcyte Echo, SPT Labtech DragonFly, Agilent BRAVO, Hamilton STAR).
* Experience using Thermo Watson LIMS.
Closing Date for Applications – December 22nd, 2024 (COB)
Please take a copy of the Job Description, as this will not be available post closure of the advert.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
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