THE ROLE
Quell is looking for a Senior Research Associate to join the Process & Analytical Research team. This individual will work in the Analytical Research sub-team to help to develop new assays and optimise current processes. The Process & Analytical Research team provides a key function to transfer knowledge and activities between the R&D and CMC departments. The successful candidate will work closely with the other sub-teams within Process & Analytical Research to conduct experiments, analyse data, and present findings. They will also collaborate with other teams in R&D and CMC to progress our understanding of our cellular products.
MAIN RESPONSIBILITIES
1. Culture primary T-cells.
2. Support optimisation of methods for Analytical Research.
3. Assess product parameters through various assays e.g. multi-parameter Flow Cytometry.
4. Isolate primary cells using immunomagnetic technologies and FACS.
5. Perform immunological cell-based assays.
6. Provide technical support for assay setup, protocol optimisation and troubleshooting.
7. Analyse data in a timely manner and present findings at team/departmental meetings.
8. Maintain highly organised and detailed documentation of experimental procedures. Collaborate and coordinate work with other teams to meet deadlines and goals.
9. Help to maintain the laboratories to a high standard.
10. Manage databases and assist in establishing relevant SOPs.
11. Provide guidance and training to new or junior staff.
Minimum Experience, Technical & Educational Requirements
EDUCATION
1. Master's degree in Immunology or related subject and 1 year or 3 years of relevant industry experience. Alternatively, Bachelor's degree in Immunology or related subject and 2 years or 5 years of relevant industry experience.
Experience & Technical Requirements – Essential (E), Preferred (P)
1. Solid understanding of cell biology. E
2. Competent understanding of immunology. E
3. Solid understanding of T-cell biology. P
4. Competent handling of mammalian and primary human immune cell cultures using aseptic techniques. E
5. Good understanding of and skilled with multi-parameter Flow Cytometry. E
6. Familiarity with data analysis software such as Prism, FlowJo and/or FCS express. E
7. Experience with immunological cell-based assays. E
8. Understanding of process optimisation and assay development. P
9. Ability to efficiently identify and implement solutions. P
10. Excellent organisational skills to adhere to deadlines and reach goals. E
11. Excellent time and project management skills aligned with an ability to prioritise activities. P
12. Ability to work co-operatively as part of a team as well as independently. E
13. Professional and personable communication skills. E
14. Good attention to detail and record keeping. E
15. Previous experience using electronic lab notebooks. P
16. Proven commitment to high quality work and maintenance of high standards. P
17. Willingness to contribute to a culture that embraces scientific excellence, integrity, urgency, patient centricity, and continuous improvement.
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