Quell is looking for a Senior Research Associate to join the Process & Analytical Research team. This individual will work in the Analytical Research sub-team to help to develop new assays and optimise current processes. The Process & Analytical Research team provides a key function to transfer knowledge and activities between the R&D and CMC departments. The successful candidate will work closely with the other sub-teams within Process & Analytical Research to conduct experiments, analyse data, and present findings. They will also collaborate with other teams in R&D and CMC to progress our understanding of our cellular products.
MAIN RESPONSIBILITIES
* Culture primary T-cells.
* Support optimisation of methods for Analytical Research.
* Assess product parameters through various assays e.g. multi-parameter Flow Cytometry.
* Isolate primary cells using immunomagnetic technologies and FACS.
* Perform immunological cell-based assays.
* Provide technical support for assay setup, protocol optimisation and troubleshooting.
* Analyse data in a timely manner and present findings at team/departmental meetings.
* Maintain highly organised and detailed documentation of experimental procedures. Collaborate and coordinate work with other teams to meet deadlines and goals.
* Help to maintain the laboratories to a high standard.
* Manage databases and assist in establishing relevant SOPs.
* Provide guidance and training to new or junior staff
MINIMUM EXPERIENCE, TECHNICAL & EDUCATIONAL REQUIREMENTS
Experience & Technical Requirements – Essential (E), Preferred (P)
· Solid understanding of cell biology. E
· Competent understanding of immunology. E
· Solid understanding of T-cell biology. P
· Competent handling of mammalian and primary human immune cell cultures using aseptic techniques. E
· Good understanding of and skilled with multi-parameter Flow Cytometry. E
· Familiarity with data analysis software such as Prism, FlowJo and/or FCS express. E
· Experience with immunological cell-based assays. E
· Understanding of process optimisation and assay development. P
· Ability to efficiently identify and implement solutions. P
· Excellent organisational skills to adhere to deadlines and reach goals. E
· Excellent time and project management skills aligned with an ability to prioritise activities. P
· Ability to work co-operatively as part of a team as well as independently. E
· Professional and personable communication skills. E
· Good attention to detail and record keeping. E
· Previous experience using electronic lab notebooks. P
· Proven commitment to high quality work and maintenance of high standards. P
· Willingness to contribute to a culture that embraces scientific excellence, integrity, urgency, patient centricity, and continuous improvement. E
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