Job Title: Research Assistant – Protein Expression (12-Month Fixed-Term Contract)
Location: West London, UK on-site full time
Please note: You must have the right to work in the UK without sponsorship until May 2026 to be eligible for this position.
About the Company:
A leading biotechnology company dedicated to transforming cancer treatment. With a strong pipeline of complex biologics and a commitment to advancing oncology research, the company fosters a collaborative and dynamic environment for scientific discovery.
Role Overview:
An exciting 12 month FTC opportunity is available for a Research Associate in Protein Expression to support the in-house protein expression platform. The role involves the design, production, and optimization of recombinant proteins and antibodies, contributing to early-stage drug discovery and preclinical development.
Essential Qualifications & Experience:
* Hands on experience with DNA constructs
* Hands on experience with transfection
* Industry experience in DNA purification at mini to giga scales.
* Proficiency in transiently expressing antibodies in CHO and/or HEK293 cells.
* Experience in optimizing expression titre and quality of antibodies and recombinant proteins.
* Familiarity with biomolecule tracking software such as Genedata Biologics.
Key Responsibilities:
* Design and construct plasmids for recombinant protein expression in suspension CHO/HEK cells, including antibodies, alternative formats, and antigens.
* Perform DNA amplification and purification from bacterial cells at various scales.
* Conduct transient expression of antibodies, ranging from milligram to gram scale.
* Produce antibodies from stable cell lines using fed-batch processes in mid-scale bioreactors.
* Explore and implement new technologies in protein expression.
* Maintain detailed records of experimental results and register expression batches.
* Collaborate with cross-functional teams.
Why Join?
* Be part of a pioneering team.
* Gain exposure to cutting-edge biotechnology in a supportive and dynamic environment.
* Work in a company committed to professional growth and inclusivity.
If you are a motivated and enthusiastic team player with a passion for protein expression and oncology research, we encourage you to apply.
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