Reimagine the infrastructure of cancer care within a community that values integrity, inspires growth, and is uniquely positioned to create a more modern, connected oncology ecosystem. We’re looking for a Senior Director of Research Sciences (epidemiology and biostatistics) to support our Custom Solutions and Services division. This individual will provide strategic scientific oversight on the design, analysis, and interpretation of RWD studies across multiple pharmaceutical customer partners leveraging Flatiron Health’s extensive tumor-specific datasets. Research Sciences provides customized RWD and RWE solutions to address the most important research questions across clinical development, market access, medical affairs and commercial use cases for our life sciences partners and internal stakeholders. What You'll Do As a Senior Director of Epidemiology and Biostatistics you will be responsible for being a collaborative thought partner with Directors/Senior Directors of RWE teams at pharmaceutical clients to design and execute impactful research studies (retrospective or prospective) to achieve strategic objectives. You will lead cross-functional teams within Flatiron including study principal investigators, project managers, medical oncologists, data scientists, and software engineers to execute these studies. You will collaborate extensively with our Life Sciences Partnerships team to provide subject matter expertise across the Flatiron Health suite of data and evidence solutions. This position requires leadership, outstanding consulting skills and an ability to understand a client’s strategic objectives and develop research solutions to achieve those objectives in a fast-paced environment. In addition you will: Engage directly with clients to understand their scientific needs, advocate for RWE solutions, and foster strong research collaborations. Act as a senior scientific leader, collaborating with Directors and Senior Directors of RWE and related functions (e.g. HEOR, Medical Affairs, Regulatory, etc.) across multiple pharmaceutical companies to align research studies with strategic objectives. Lead cross-functional, project-based teams—including principal investigators, project managers, medical oncologists and clinical directors, statistical programming, and data curation teams—to ensure seamless research execution, balancing scientific rigor with an exceptional customer experience throughout the study lifecycle. Serve as a key scientific advisor guiding interpretation of studies, relevance to various stakeholders, and implications for strategic objectives Expand the scope of research questions and stakeholder engagement within a portfolio of pharmaceutical, biotechnology or medical device accounts, ensuring impactful insights that align with investment levels. Lead and mentor a team of 3-5 individuals, fostering a culture of scientific excellence, collaboration, and professional growth. Who You Are You have a PhD degree in Epidemiology or Biostatistics (or a related field), plus 12 years of experience (or a Master’s degree with 15 years of experience) in retrospective and/or prospective real-world, observational research. Extensive experience in a consulting environment leading to successful collaborations over several years with pharmaceutical companies You have experience leading large, high visibility engagements encompassing a spectrum of solutions including (but not limited to) RWE generation for regulatory submissions, multi-dataset trials, and patient-reported outcomes studies. You have deep knowledge of the oncology RWD/E ecosystem, use cases, and epidemiologic methods You have a deep understanding of cancer, approaches to treatment, study design in oncology, and emerging technologies in cancer therapeutics. You have a deep understanding of RWE methods including (but not limited to) matching, stratified analyses, and causal inference. You have worked in a matrix-structured environment with multiple functional divisions. You are able to handle multiple tasks concurrently, to meet ongoing deadlines in a fast-paced environment. You are an excellent communicator, with experience drafting and developing complex, technical documentation and delivering presentations to scientific audiences. Extra Credit You have experience in global retrospective trials You have experience in applying AI approaches to evidence generation You have experience in multi-omic datasets including genomics and imaging data