3 Years fixed term A 3-year Research Technician post is available at the MRC Laboratory of Medical Sciences (LMS) within the Metabolism in Immunity, Cancer and Ageing (MICA) group headed by Nazma Malik. The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus. We are seeking an enthusiastic and creative technician with a background in biochemistry, cell biology, cancer, metabolism, and/or immunology to join the MICA group. In this role, you will assist in developing tools and experimental approaches to investigate the impact of AMPK metabolic pathways on immunity and tumour immune responses in human cell cultures and animal models. To begin with, your primary responsibilities will include perturbing metabolic networks in cell lines using Crispr/Cas9 methods and helping with the analysis of phenotypes using a variety of biochemical techniques, fixed and live cell imaging, and proteomics. The ideal candidate should possess extensive experience in molecular cloning, Crispr/Cas9 methods and biochemical techniques. In vivo experience would be an advantage. You should have strong organizational skills to assist with general lab maintenance and the ability to collaborate effectively within the MRC-LMS and with external partners when required. For more information about our work, please visit Metabolism in Immunity, Cancer and Ageing (MICA) - LMS Laboratory of Medical Sciences (mrc.ac.uk) The successful candidate should have a degree in an appropriate subject and research experience, ability to organize time effectively, prioritize and work to deadlines. Please refer to the Job Description and Person Specification online for further information about the position. We offer a wide range of employee benefits, including 30 days annual leave, a defined benefit pension scheme, family friendly policies, and support with CPD. For more details, visit benefits of working for UKRI. We are committed to advancing EDI and as "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy. Learn more about some of our workplace inclusion initiatives. This role does not meet the eligibility requirements for Skilled Worker visa certificate of sponsorship under UKVI legislation. Therefore, we will not be able to sponsor individuals who require right to work in the UK to carry out this role. For full details of this post and to complete an online application, please click on the ' Apply ' button above and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. Please quote reference number LMS 2519. Closing date: 24 November 2024 The Medical Research Council is an Equal Opportunities Employer Final appointment will be subject to pre-employment screening. £29,808 to £31,671 plus London allowances (£3,913 & £1,472) per annum London, UK