Associate Scientist – Target Discovery | Biotech | CHO Cell Lines | CRISPR
Location:Oxford
We’re hiring an Associate Scientist to join an innovative biotech team focused on advancing mammalian cell line development. If you're experienced in CHO cell culture and CRISPR gene-editing, and you're passionate about target discovery, this could be your next move.
What you’ll be doing:
* Designing and executing CHO cell culture experiments using small-scale and high-throughput models
* Running CRISPR knockout screens and transfections for gene editing
* Applying molecular and cell biology assays (qRT-PCR, Western blotting, ELISA)
* Operating the BD FACSAria Fusion Flow Cytometer for single cell cloning and analysis
* Supporting cell line development using technologies like Beacon and Ambr15
* Writing SOPs, maintaining lab documentation, and training junior scientists
* Ensuring lab safety standards and participating in out-of-hours cell culture as needed
What we’re looking for:
* BSc/MSc with 3+ years or PhD with 1+ years in a biotech or pharma environment
* Strong experience with CHO suspension cells, single-cell workflows, and genotyping
* Skilled in CRISPR/Cas9 techniques and FACS-based cell sorting
* Comfortable working independently and collaboratively in a fast-paced lab
* Experienced in experimental planning, troubleshooting, and scientific communication
Nice to have:
* Familiarity with Beacon, Ambr15, or 96-well high-throughput models
* Experience working safely with lentiviral plasmid systems in a CAT2 environment
* Understanding of monoclonal antibody production and critical quality attributes (CQA)
Looking to play a key role in breakthrough biologics research? Apply now!
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