Site Name: UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence
Posted Date: Mar 6 2025
Director, Translational Research Leader (Oncology)
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.
We are seeking a highly experienced and motivated Director to lead a team of oncology translational scientists within the Oncology R&D department. Leveraging your extensive experience in oncology translational research (particularly in early-stage drug development), you will be leading multi-disciplinary teams in a matrix environment as well as managing and developing high performing teams.
Key Responsibilities include, but are not limited to:
* This role requires strong leadership skills along with deep translational research expertise as it is expected that the person will have decision making accountability for defining what translational work is conducted on the projects/alliances to which they are assigned, as well as the ability to communicate these translational plans in a clear, confident and succinct manner to cross functional matrix teams.
* Leveraging deep expertise in cancer biology and the oncology clinical landscape, represent Oncology Translational Research (OTRO) as a translational lead in cross-functional matrix teams.
* Independently create translational research plans, implemented/delivered through both matrix and line leadership, to address key asset team questions around mechanism, biomarkers (pharmacodynamic, response and/or resistance) and combination/indication expansion opportunities.
* Act as a translational advisor to preclinical project teams to enable early biomarker discovery/evaluation, indication selection, competitive differentiation and enable clinical transition plans.
* Engage with external HCPs/Investigators globally through translational alliances to design and lead efforts for deep profiling of existing clinical cohorts/biobank material that will generate insights to guide future clinical studies.
* Lead and mentor a team of highly skilled translational leads, fostering a collaborative and innovative environment that promotes scientific excellence and professional growth.
* Demonstrate exceptional interpersonal skills to build relationships with internal Oncology Translational Research teams and with cross-functional partners in disciplines across GSK as well as external partners, to lead the conduct of translational studies and ensure seamless integration of translational research efforts.
* Communicate translational research progress and findings to key stakeholders, including senior leadership and external collaborators, through written reports and presentations and contributing to regulatory documents.
* Must be able to manage multiple projects and workstreams, including assessment of workload and resourcing requirements to deliver the team’s objectives.
* Maintain an up-to-date knowledge of the clinical and translational research landscape in the areas you are representing as a translational leader.
Why you?
Basic Qualifications & Skills:
* Extensive experience in translational research, with significant experience in oncology drug development (particularly early stage) is essential.
* Proven record of leading multi-disciplinary teams in a matrix environment as well as managing and developing high performing teams is essential.
* Prior demonstration of having cross functional knowledge of cancer biomarker discovery with experience in the use of non-clinical translational experimental approaches as well as reverse translation activities to address key mechanistic and biomarker questions.
* PhD or equivalent experience in Life Sciences.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
* Scientific excellence and deep understanding of cancer biology, as evidenced by publications, research reports, and external presentations.
* Experience in Antibody Drug Conjugate and/or T-cell Engager research and development.
* Experience in molecular and genomic assay technologies and with clinical assay development (e.g. flow cytometry, immunohistochemistry, immunoassays).
* Experience in managing research collaborations.
Closing Date for Applications – 13th March (COB)
Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
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