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Postdoctoral Fellow | Generative and Synthetic Genomics, Cambridgeshire
Location: Cambridgeshire, United Kingdom
Job Category:
Other
EU work permit required:
Yes
Job Reference:
414c31b1afb8
Job Views:
8
Posted:
02.03.2025
Expiry Date:
16.04.2025
Job Description:
Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.
We have an exciting opportunity for a Postdoctoral Fellow to join the Parts Group on a 3-year fixed-term contract. Our group is part of the new Generative and Synthetic Genomics Programme, a wonderful environment for using engineering at scale to understand the human genome and combining the massive datasets generated with machine learning models.
We are looking for a new colleague to lead one area of research that can come from our list of open and ongoing challenges or be defined by you.
About the Role
As a Postdoctoral Fellow you will be responsible for:
* Planning and executing a research project in collaboration with the team leader that is original and leverages the unique scaling opportunities at the Institute.
* Leading on publications and presenting your data at lab meetings, national and international conferences.
* Seeking training (including for transferable skills) as well as taking part in training organised for Postdoctoral Fellows.
About Us
Our research seeks to understand the function of human DNA through engineering, with support for scaling from core pipelines as well as our research specialists. We have specific projects around manipulating DNA in human cells at scale: deleting large chunks of non-coding DNA, inserting large amounts of ectopic DNA, and randomising stretches of existing DNA, all to inform generative models of human DNA function.
Some example projects include:
* Resolution of a human super-enhancer by targeted genome randomisation
* Engineering structural variants to interrogate genome function
* Randomizing the human genome by engineering recombination between repeat elements
About You
Your work will help shape future research questions and methodology in the lab. You will have the ability to work independently as well as part of a collaborative multi-disciplinary team.
Essential Skills:
* PhD in Molecular Biology, Bioinformatics, Physics, Engineering or related relevant field
* Evidence of good productivity through publications
* Motivation to understand function of DNA in human cells using engineering and modelling approaches
* Ability to work as part of a team
* Highly developed problem-solving skills
* Excellent communication skills as evidenced by presentations
* Ability to prioritise tasks
* Demonstrates inclusivity and respect for all
Joining us as a Postdoctoral Fellow
You will be part of a vibrant international Postdoctoral Fellow community at the Sanger Institute with a wide programme of transferable skills training and excellent career development opportunities. We are committed to:
* Providing an enriching and respectful research environment so you can focus on and enjoy your work
* Mentoring you and providing opportunities for you to network across the genomics scientific community
Additional Information
Please apply with your CV and a Cover letter outlining how you meet the criteria set out above.
Salary per annum: £38,000 - £49,156 (dependent upon skills and experience)
Closing Date: 02-MAR-25
Contract duration: 3 years fixed term
Hybrid Working at Wellcome Sanger:
We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.
Equality, Diversity and Inclusion:
We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We have a supportive culture with the following staff networks: LGBTQ+, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness. The networks are also a place for allies to provide support to others.
We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work. That's why we're committed to creating a truly inclusive culture at Sanger Institute. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.
Our Benefits:
We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme. The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute. #J-18808-Ljbffr