Opportunity in Antigen Discovery
Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.
Our client is a leader in antigen modulation through ERAP enzyme inhibition, with an ERAP1 inhibitor in Phase I/II clinical trials and another expected to enter Phase I for autoimmune indications in 2025. They are advancing a hit-to-lead program targeting ERAP2 and exploring the translational potential of ERAP enzyme inhibition.
Job Responsibilities
* Design and implement innovative data analysis strategies to advance the antigen discovery pipeline.
* Analyze large-scale datasets, including immunopeptidomic, transcriptomic, and genomic data, to identify ERAP1 inhibitor-dependent targets.
* Collaborate with a multidisciplinary scientific team to oversee all aspects from in-silico antigen discovery to experimental validation.
Requirements
* PhD in bioinformatics, immunology, computational biology, or a related field.
* Expertise in mass spectrometry-based proteomics data acquisition and processing, with familiarity in data-dependent and data-independent methods.
* Strong knowledge of machine learning and/or multivariate statistical modeling.
* Proficiency in R or Python programming.
* Experience in large-scale bioinformatics analysis of omics data.
* Ability to analyze, interpret, and record findings efficiently and in compliance with standards.
* Strong communication skills, capable of conveying complex topics to diverse audiences.
Additional Information
The successful candidate will have a deep understanding of antigen processing and be able to contribute to the company's overarching goals. The salary for this position is estimated at $120,000 per annum, depending on location and experience.