Internal candidates only We are seeking a postdoctoral Research Associate with a strong interest in haematopoietic transcription factors and experience spanning wet lab and computational biology to join the group of Professor Brian Huntly in the Department of Haematology and Cambridge Stem Cell Institute ( https://www.stemcells.cam.ac.uk/people/pi/huntly ). Our group studies the mechanisms of transcriptional and epigenetic dysregulation that drive leukaemia and lymphoma, and how these programmes are subverted from their normal role in haematopoietic stem cells and their progeny. We combine functional and genomic experiments in experimental model systems and patient samples to identify pathological mechanisms, therapeutic targets and novel therapies (e.g. Shah et al, Blood, 2024; Lara-Astiaso et al, Nature Genetics, 2023; Agrawal-Singh et al, Blood, 2023). We are highly productive, internationally recognised and enjoy collaborations worldwide. You will complete an ongoing project studying the role of the PU.1 transcription factor in the maintenance of acute myeloid leukaemia using proteomic, transcriptomic, genomic and functional approaches with cell line, murine and patient derived models and samples. Experience of studying transcription factors and haematological malignancies is required, as is experience of proteomic, transcriptomic, genomic and functional studies. The project makes extensive use of bioinformatics integrate multi-omics data. Experience of bioinformatics is required together with a willingness to receive further training in this area. Cambridge is one of the best places in the world to be a biomedical scientist. The Cambridge Biomedical Campus is the largest biomedical research campus in Europe and offers unique opportunities for collaboration. Links with industry abound, with major biotech companies, including AstraZeneca, basing their operations here. You will be based in the University of Cambridge's £94m flagship Jeffrey Cheah Biomedical Centre and through membership of the Cambridge Stem Cell Institute, CRUK Cambridge Centre and Cambridge Haematological Malignancies Virtual Institute have access to outstanding core facilities for your research. Informal enquiries to Brian Huntly at bjph2cam.ac.uk. Fixed-term: The funds for this post are available until 28 February 2026 in the first instance. Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online Application form. Please include details of your referees, including email address and phone number, one of which must be your most recent line manager. The closing date for applications is: 12th February 2025 The interview date for the role is: Week beginning 17th February 2025 Please quote reference RB44887 on your application and in any correspondence about this vacancy. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Further information Further Particulars Apply online