RDM Investigative Medicine, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford About the Role We are seeking to appoint a post-doctoral scientist with experience in intestinal epithelial organoid culture to join Prof. Alison Simmons’s lab to investigate mechanisms of barrier regeneration and repair.The post will involve culturing and scaling human epithelial organoid cultures to explore novel biological hypotheses as to the effect of specific mediators on intestinal barrier biology. The post-holder will work with group members to use a series of cutting-edge technologies to address this question. About the Radcliffe Department of Clinical Medicine The Simmons group is based in the Translational Immune Discovery unit at the Weatherall Institute of Molecular Medicine and is at the forefront of intestinal disease biology. The group takes a multi-faceted approach that incorporates molecular, biochemical and computational approaches to address intestinal disease pathogenesis and develop new approaches to treatment. What We Offer Flexible working An excellent contributory pension scheme 38 days’ annual leave (including bank holidays) A comprehensive range of childcare services Family leave schemes Cycle loan scheme Discounted bus travel and Season Ticket travel loans This is a full-time appointment funded for 1 year by Thelior Bio, with the likelihood of extension. Applicants must hold a relevant Ph.D/D.Phil with post-qualification research experience. Application process Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on 21/10/2024 will be considered. £37,524 to £45,763 p.a