We are seeking an enthusiastic and highly motivated individual to work on a British Heart Foundation funded research project investigating novel therapies aimed at preventing graft failure in coronary artery bypass surgery. Using cellular and molecular biological approaches, the aim of this project is to investigate endothelial cell (EC) heterogeneity factors regulating vascular cell connectivity with a particular focus on their regulation and posttranslational modification by nitric oxide and ubiquitin. The applicant will work closely with the PI within the Wellcome-Wolfson Institute for Experimental Medicine. The successful applicant will be involved in developing methods to investigate the regulation of EC heterogeneity factors using a broad range of systems and techniques. About the person: The successful candidate must have and your application should clearly demonstrate that you meet the following essential criteria: Have or about to obtain a PhD in vascular biology, cell/ molecular biology, biomedical science or a closely related area. PhD must have been submitted by the date of appointment. Relevant recent hands-on research experience in cell or molecular biology using appropriate model systems. Recent and relevant hands-on experience in molecular cell biology techniques demonstrated through publication or presentation. To include three of the following: Isolation or culture of mammalian cells. Cellular and molecular biology techniques such as western blotting, qPCR, gene knockdown/ overexpression. Appropriate in vitro functional assays. Appropriate in vivo models. Your application should clearly demonstrate how you meet the essential and, where applicable, desirable criteria. This is an ongoing project and additional funding will be sought to extend the contract beyond the initial 35 months advertised here. To be successful at shortlisting stage, please ensure you clearly evidence in your application how you meet the essential and, where applicable, desirable criteria listed in the Candidate Information. Fixed term contract posts are available for the stated period in the first instance but in particular circumstances may be renewed or made permanent subject to availability of funding. What we offer: Beyond a competitive salary, the University offers an attractive benefits package including a holiday entitlement of up to 8.4 weeks a year, pension schemes and development opportunities. We support staff wellbeing with flexible working options, work-life balance initiatives and support for physical and mental health. You can find more detail on all of this and more on our website. Queen's University is committed to promoting equality of opportunity to all. We subscribe to Equality Charter Marks such as the Diversity Charter Mark NI and Athena Swan and have established staff networks such as iRise (Black, Asian, Minority Ethnic and International Staff Network) and PRISM (LGBTQ) which help us progress equality. For further information on our commitment to Equality, Diversity and Inclusion, please visit our website. £39,922 to £41,112 per annum