We are seeking to appoint a Senior Postdoctoral Research Scientist in Bioinformatics to develop a predictive algorithm for immunogenicity based on biological mechanism. GlaxoSmithKline and Oxford University (GO) launched the PRECIsE Alliance in 2025 with the aim of conducting deep exploration of precancers to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is directed by Prof Sarah Blagden and theme leads Professors Tim Elliott, Ellie Barnes and Simon Leedham. Within Oxford, the alliance spans multiple departments and networks basic science immunology and clinical development expertise as well as community engagement. This truly multi-disciplinary initiative seeks to transform cancer by actively preventing it from developing, initially in people at highest risk of the disease and later in the wider population.
It is essential that you hold a PhD in mathematical immunology, or related discipline, and have experience of multiple mathematical modeling approaches applied to biology (eg dynamic systems, agent-based, statistical). You will also have experience of bioinformatics / computational biology as well as extensive coding experience in multiple languages (R essential). You will have evidence of scientific creativity, and an ability to contribute to determining future directions for the research project, and the ability to take initiative in developing and troubleshooting new techniques. Good organisational skills and the ability to multitask effectively, and strong written and oral presentation skills, and effective communication skills are essential to the role. Research experience in antigen presentation, with proven research skills in this field is highly desirable.
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