Description Position Details Department of Cancer and Genomic Sciences, School of Medical Sciences, College of Medicine and Health Location: University of Birmingham, Edgbaston, Birmingham UK Clinical salary Full Time, Fixed Term contract up to 4 years Closing date: 12th December 2024 2 positions available Role Summary We are recruiting two Clinical Research Fellows as PhD students in the area of paediatric oncology. The appointees will be registered on the ‘The Azaylia Childhood Cancer PhD Programme’, with funding available for up to 4 years. The two appointees will undertake project-specific research and training in this area as part of an established academic team on one of the following projects: Project 1: Linking phenotype to genotype in paediatric Acute Myeloid Leukaemia with GATA2 mutations. Supervised by Dr Rui Monteiro. In this project, the candidate will be investigating how different GATA2 mutations found in paediatric AML affect blood stem cell function and predispose to the onset of leukaemia. Project 2: Identifying therapeutic vulnerabilities in paediatric AML harbouring KMT2A rearrangements. Supervised by Dr Paloma Garcia. In this project, the candidate will be investigating how different KMT2Ar mutations found in paediatric patients affect treatment response. Candidates may indicate whether they wish to be considered for one or both projects. Their main objective is to produce international quality research data and present a thesis for PhD viva voce examination. These posts align with current strategy in the Department of Cancer and Genomic Sciences to strengthen in the areas of clinical oncology and translational cancer research in Birmingham. It is an expectation that the appointees will help establish stronger links between the Birmingham Children’s Hospital and The University of Birmingham and enhance, directly, translational research capacity within the Department. Main Duties To plan and develop research contributions to subject area using methodologies, critical evaluations, interpretations, analyses and other appropriate techniques To suggest and contribute to the development of research techniques, models and methods in collaboration with colleagues To disseminate research findings using appropriate and effective media such as publication, research seminars, attendance at conferences etc To contribute to the production of research reports and publications To analyse and interpret the results of own research and generate ideas based on outcomes Promotes equality and values diversity acting as a role model and fostering an inclusive working culture Required Knowledge, Skills, Qualifications, Experience Medical degree, (optional) membership of one of the Royal Colleges Appropriate levels of medical training (ST1-ST4) with an interest in haematology, oncology, paediatric haematology or similar area Possesses Research experience in a wet lab setting Possesses sufficient breadth and depth of specialist knowledge to undertake both clinical responsibilities and research within established research programmes Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day-to-day activity in own area that those with protected characteristics are treated equally and fairly. Dimensions The student will be part of an academic Team comprising at least two senior academics who will act as project supervisors. The team might also comprise post-doctoral fellows, technicians and other PGR students. Planning and Organising Plan for the use of research resources as appropriate Contribute to the planning of research projects Co-ordinate own work with others to avoid conflict or duplication of effort Problem Solving and decision making The direction of the research will be determined by the academic supervisory team in discussion with the student Internal and External relationships Liaise with research and support staff on routine matters and with staff within clinical department OH/DBS required The University is committed to safeguarding and we promote safe recruitment practice, therefore all associated pre-employment checks will be undertaken before any appointment is confirmed. Due to the nature of the work undertaken in this role all successful applicants will be subject to a satisfactory Occupational Health and DBS clearance prior to appointment. Further particulars can be found here Informal enquiries to Project Supervisor Dr Paloma Garcia, email: P.Garciabham.ac.uk or Dr Rui Monteiro, email: R.Monteirobham.ac.uk We believe there is no such thing as a 'typical' member of University of Birmingham staff and that diversity in its many forms is a strength that underpins the exchange of ideas, innovation and debate at the heart of University life. We are committed to proactively addressing the barriers experienced by some groups in our community and are proud to hold Athena SWAN, Race Equality Charter and Disability Confident accreditations. We have an Equality Diversity and Inclusion Centre that focuses on continuously improving the University as a fair and inclusive place to work where everyone has the opportunity to succeed. We are also committed to sustainability, which is a key part of our strategy. You can find out more about our work to create a fairer university for everyone on our website .