About the role
The Group of Brain Vasculature and Perivascular Niche focuses on vascular growth and the development of blood vessels ( angiogenesis ) in the brain, including endothelial cells and perivascular cells of the neurovascular unit/perivascular niche, and on brain vascular heterogeneity in development, health and disease: The main aims are: i) to understand the cellular and molecular underpinnings that govern the growth of the developing, adult, and diseased human brain vasculature at single-cell resolution, ii) to uncover the single-cell transcriptomic, genomic and epigenomic landscapes and spatial biology of the developing, adult and diseased human brain vasculature, iii) to elucidate how developmental programs regulate vascular growth/angiogenesis in the human brain tumour vasculature (patho-fetal axis / onco-fetal axis), iv) to unravel the onco-fetal programs of vascular growth/angiogenesis and immunosuppression/immunomodulation, and v) to translate these fundamental insights about the onco-fetal axis in the human brain (tumour) vasculature into clinical settings with the ultimate goal to identify novel therapeutic strategies for human brain tumours (and for other vascular-dependent diseases such as human brain vascular malformations).
The post is funded for until 31st October in the first instance, with possibility of extension.
About you
The successful candidate is be expected to be a driving force of these highly novel, original and competitive projects, to produce independent and original research in this area, to develop and apply new concepts and to have a creative approach to problem solving.
Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
What we offer
As well as the exciting opportunities this role presents we also offer some great benefits some of which are below:
1. 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days)
2. Defined benefit career average revalued earnings pension scheme (CARE)
3. Cycle to work scheme and season ticket loan
4. On-Site nursery
5. On-site gym
6. Enhanced maternity, paternity and adoption pay
7. Employee assistance programme: Staff Support Service
8. Discounted medical insurance