Laboratory Research Scientist - Genomics STP
Salary for this Role:
From £31,675 per annum
Job Title: Laboratory Research Scientist - Genomics STP
Reports to: Jerome Nicod
Closing Date: 20/Nov/2024 23.59 GMT
Job Description:
Genomics STP
Reports to: Head of Genomics STP
This is a full-time, permanent position on Crick Terms and Conditions.
OVERVIEW
The Genomics Science Technology Platform (Genomics STP) is a core-funded laboratory comprised of a team of 21 scientists who provide Next Generation Sequencing (NGS) support to over one hundred research groups at the Crick. These labs work at the cutting edge of biomedical science in disciplines such as cancer, infectious disease, immunology, neurology, and developmental biology. Next generation sequencing has revolutionised approaches to biology, making this a key technology for a large proportion of the pioneering research groups based at the Crick. Located in the heart of London - and hosting the latest sequencing platforms - our team carries out all aspects of NGS from project design and execution, through to delivery of the sequence data for analysis.
The Genomics STP is now looking to recruit an enthusiastic molecular biologist to join its team of genomics experts. The successful applicant will help the team in its mission to deliver high quality data with rapid turnaround time. The post holder will assist with sample submission, quality control, library preparation and sequencing following standard operating procedures (SOPs) and automation when appropriate.
KEY RESPONSIBILITIES
These include but are not limited to:
* Support diverse research projects across the Institute using genomics technologies
* Prepare Next Generation Sequencing libraries following standard operating procedures
* Operate Illumina and Oxford Nanopore Technologies sequencing platforms
* Operate robotic sample preparation instruments
* Perform single cell and spatial omics experiments using established protocols
* Keep accurate laboratory records
* Assess results of individual projects and suggest improvements based on performance
* Liaise with equipment providers for standard problems and issues
* Keep up-to-date with the rapid evolution of the field through literature, training and attendance to conferences and workshops
* Participate in developing methods and techniques in collaboration with team members and Crick researchers
* Be responsible with team members for the daily housekeeping of the laboratory area.
KEY EXPERIENCE AND COMPETENCIES
Essential:
* Degree in biological sciences or equivalent.
* Strong background in cell biology and molecular biology
* In depth understanding of library preparation for Next Generation Sequencing, including quality control and troubleshooting/optimisation.
* A good understanding of the latest applications and technologies pertaining to human genomic research.
* A high degree of self-motivation to maintain workload with minimal supervision
* Excellent work ethic, including attention to detail and care for high standards
* Flexible and cooperative approach to work well in a team
* Proactive, showing initiative and independent thought
* Proven ability to keep good and accurate records
* Good time management and ability to manage multiple projects simultaneously
* Excellent communication skills at all levels
* Flexibility to work in a fast-paced environment and occasionally outside regular hours
Desirable:
* Hands-on knowledge of library preparation using DNA and RNA from various sources.
* Experience working in a genomics/sequencing core facility in an academic or industrial setting, or similar.
* Familiar with the daily use of a Laboratory Information Management System (LIMS)
* Experience with single cell applications
* Demonstrated experience with Spatial Technologies platforms.
* Experience with high throughput methods, ideally including laboratory automation.
ABOUT US
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease.
Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here: Pay and Benefits
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities.
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