Xias Bio are seeking an experienced Scientist to support new and existing product development as the company expands its portfolio. This role will be primarily laboratory-based. The ideal applicant would have worked in microbial strain construction, fermentation, recombinant protein expression and purification, and/or Synthetic Biology. She or he would be able to work with minimum supervision and guidance. The job will be fast-paced with parallel projects on-going, but with exciting outcomes along the way. As Senior Scientist, you will conduct complex research on fermentation (with a focus on the development of new bioprocesses and the optimization of existing processes), design and execute experiments to improve expression strains and optimize downstream processes (protein purification). The nature of the work will mean that from time to time this may include working with flexible hours and carrying out tasks other than those outlined below.
Key duties and responsibilities of the role:
* Independently lead research project/s for product development
* Microbial strain construction
* Optimization of microorganism fermentation
* Protein engineering and development of biochemical assays to measure/test functionality and activity
* Protein purification and characterization
* Providing training, advice and mentoring to other scientists
* Detailed recording, independent analysis and interpretation of data and results, drawing out of conclusions and strategic recommendations
* Writing and reviewing SOPs, reports and other related documentation
* Presenting results to the team to update on project’s progress
* Contribute to Xias Bio’s growing product portfolio
* Remaining up-to-date on relevant methods and scientific literature
* Strong practical knowledge of Molecular Biology methods, including plasmid construction, microbial transformation and genotyping + practical knowledge of high-throughput cloning methods
* Flawless aseptic technique and sterile culturing of microorganisms
* Practical experience growing/cultivating yeast or bacteria
* Methods of microbial strain construction and/or optimisation
* Experience with different scales of microbial fermentation (0.5-5L and >15L)
* Proficiency in developing, troubleshooting, and executing biochemical assays
* Ability to work independently, being resourceful, and proactive in solving complex problems, including knowing when to seek help
* Comfortable when juggling multiple tasks efficiently and prioritizing workload
* Impeccable scientific and work ethics, diligent notebook-taking, well-organized, and with attention to detail
* Excellent presentation and communication skills
* Highly motivated, team-oriented individual with a can-do attitude to problem-solving using novel approaches
Requisite education, experience, and minimum qualifications for this role:
PhD in Microbiology, Molecular Biology, Synthetic Biology, Metabolic Engineering, Protein Engineering, Biochemistry, Bioprocess engineering, Biology, or related fields with industrial experience (preferable)
Reports to: Chief Scientific Officer
Remuneration: commensurate with experience
Holidays: 25 days + Glasgow Bank Holidays + Birthday
Benefits: Pension scheme, casual dress, path for career progression
Apply: Please submit your CV and cover letter to recruitment@xiasbio.com
Schedule: Monday to Friday
Xias Bio is an equal-opportunity employer.
Strictly no agencies.
#J-18808-Ljbffr