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Job Description
This multi-institutional Dual PhD project between the University of Liverpool and the National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India, aims to develop quantitative magnetic resonance imaging and spectroscopic imaging biomarkers to assess abnormalities in neural function and metabolism in well-established preclinical models of neurological disorders. Specifically, the project will initially develop and validate longitudinal diffusion tensor tractography and MR spectroscopy in a Trappc9 knockout model of intellectual disability, which demonstrates microcephaly and learning disabilities.
Responsibilities
1. Development of quantitative imaging biomarkers for characterization of neural functional abnormalities in preclinical models of neurodevelopmental disorders.
Further Information
Applications should be made to the project supervisors, Harish Poptani (harishp@liverpool.ac.uk) or Antonius Plagge (plagge@liverpool.ac.uk), in the first instance via CV and cover letter.
Candidates will be invited to interview with UoL and NIMHANS. Both Parties must approve the admission, in line with the terms of the Dual PhD Programme.
The successful candidate should then submit a formal application through the University online application form here.
Please specify on your application that you are applying for the NIMHANS Dual PhD Programme.
Start date will be determined after formal approval from both partners and in consideration of the NIMHANS Dual PhD Agreement.
Training
The project will provide training in several strategic areas including quantitative skills in neuroimaging, metabolism, behavioural biology and experimental design involving animals. In addition, interdisciplinary skills such as preclinical imaging, genotyping, behaviour assays, histology and immunohistochemistry will also be provided by the supervisory team.
Eligibility
Applicants must have a Master’s degree in either biomedical sciences, bioengineering or a relevant field. Due to funding restrictions, only UK citizens or residents with permanent residency in the UK are eligible to apply (applicants must be classed as HOME for fee purposes). The successful candidate will commit to spending up to two years at the University of Liverpool and up to two years at NIMHANS in Bengaluru (India). The expected pattern of study for this studentship is Year 1 and Year 2 based in Liverpool and Year 3 and Year 4 based in India.
Contact Details
Prof Harish Poptani: harishp@liverpool.ac.uk
Dr Antonius Plagge: plagge@liverpool.ac.uk
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