Background Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations. Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more. To find out more, please visit www.sygnaturediscovery.com. About the role Sygnature Discovery is seeking an experienced Lead Scientist to join our In Vivo Pharmacology group. The In Vivo Pharmacology group currently consists of >30 highly trained staff. The group delivers high quality pharmacology studies in the areas of CNS, Metabolic (obesity, diabetes), Inflammation and DMPK. Sygnature Discovery is a Contract Research Organisation (CRO) with laboratories in the UK and North America with a track record for delivering high quality data to a growing number of clients working in the drug discovery space from early target discovery efforts to IND enabling studies. In the In Vivo Pharmacology Group our workdays can be quite dynamic with rapid changes, which means flexibility and supporting and assisting team members is essential. Your tasks as a Lead Scientist within the Technical team will be varied and will involve daily operational work conducting in vivo studies and managing/mentoring other team members. Main duties and responsibilities: Delivering high quality data and supporting documentation through performance of In Vivo studies (dosing, sampling, tissue collection) Experience of surgical procedures (e.g. vessel cannulations) Acting as a mentor, coach, and role model for other research scientists, providing experimental guidance and support as appropriate. Key requirements: Ideally, a relevant education such as BSc in pharmacology, biology or Higher IAT Qualification. Thorough understanding of the Animals (Scientific Procedures) Act 1986 Extensive experience in an In-Vivo work-related background. Home Office Personal Licence PIL A, B & C. The proven ability and desire to carry out in vivo work (e.g. administration of substances, behavioural experience, surgery experience) Excellent verbal and written communication skills, with the ability to interact effectively with internal and external stakeholders. Strong organisational, interpersonal and time management skills, the ability to problem solve, and work both independently and collaboratively with the team Self-motivated, well organised, able to prioritise tasks, delegate tasks and work to deadline pressure Ability to execute projects to tight timelines with the ability to adapt to rapid changes in project priorities Benefits Here at Sygnature Discovery, we take pride in offering an excellent training and benefits package. As a valued employee, you will be entitled to: - 25 days annual leave (rising with service) plus bank holidays, and buy/sell scheme - Private Medical Insurance - Life Insurance - Employee Assistance Programme and mental health first aiders - Enhanced Family Friendly Policies - Sygnature Group Pension Scheme - 1 paid volunteer day per year - A host of flexible benefits to support your wellbeing and lifestyle Why Sygnature Discovery At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide. We understand the importance of creating a work environment that empowers you to thrive. That’s why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth. We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work. If you’re interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis. If you have any questions or need further information, please contact the Talent Acquisition team at careerssygnaturediscovery.com. Please do not submit your application to this email address For more information on life at Sygnature Discovery, visit www.sygnaturediscovery.com/careers