RDM Investigative Medicine, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford About the Role We are seeking to appoint a post-doctoral scientist to join Prof. Alison Simmons’s lab to investigate mechanisms of intestinal fibrosis. Capitalising on a large data resource documenting intercellular signalling circuits and gene regulatory networks driving pathogenic cell states linked to intestinal inflammation this post will involve exploring novel biological hypotheses as to the induction and persistence of intestinal fibrosis; with use of advanced model systems and a series of cutting-edge technologies to address this question. About the Radcliffe Department of Clinical Medicine The Simmons group is based in the Translational Immune Discovery unit at the Weatherall Institute of Molecular Medicine and is at the forefront of intestinal disease biology. The group takes a multi-faceted approach that incorporates molecular, biochemical and computational approaches to address intestinal disease pathogenesis and develop new approaches to treatment. What We Offer Flexible working An excellent contributory pension scheme 38 days’ annual leave (including bank holidays) A comprehensive range of childcare services Family leave schemes Cycle loan scheme Discounted bus travel and Season Ticket travel loans This is a full-time appointment funded for 2 years by The Helmsley Trust, with the possibility of extension. Applicants must hold a relevant Ph.D/D.Phil with post-qualification research experience. Application process Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on 21/10/2024 will be considered. £37,524 to £45,763 p.a