Drug Design Chemistry Lead, London
Isomorphic Labs is a new Alphabet company that is reimagining drug discovery through a computational- and AI-first approach.
We are on a mission to accelerate the speed, increase the efficacy and lower the cost of drug discovery. You'll be working at the cutting edge of the new era of 'digital biology' to deliver a transformative social impact for the benefit of millions of people.
Come and be part of a multi-disciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring, collaborative and entrepreneurial culture.
Your impact
As part of the ongoing expansion of our Drug Design and Medical Research function, we are looking to recruit a number of Medicinal Chemistry positions in our Drug Design team.
You will be supporting the business alongside world leading AI/ML Drug Design Platform teams. You will collaborate to deliver scientific expertise and strategic direction to drive both improvements in the Platform and apply this to real drug design projects.
As a member of the Drug Design team you will be responsible for cross-functional strategic alignment and effective resource allocation in support of the delivery of integrated drug discovery projects leveraging significant external CRO resources.
If you are a skilled and ambitious scientist looking to take the next step in your career, joining the Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.
What you will do
* Take on a lead chemist role or project leader (depending on experience) in one or more drug discovery programs, responsible for the overall chemistry strategy and compound design.
* Apply your knowledge and track record of modern drug design / discovery principals and synthetic organic chemistry to provide strategic input and technical direction to our Platform teams and to execute Drug Design programs.
* Collaborate both internally and with third party organisations interacting within multidisciplinary teams to support data-driven delivery of high quality scientific solutions to complex technical problems
* Represent the company externally, interacting with existing and prospective collaborators and Contract Research Organisations (CROs)
* Manage CRO resource and other members of the growing team, mentoring and supporting their development
* Prepare detailed scientific proposals and reports to support new and ongoing programs
* Embrace and champion our culture of inclusion and continuous professional development
Skills and qualifications
Essential:
* PhD in Chemistry, or a related technical field, or equivalent experience
* 6+ years in pharma or biotech working in different therapeutic areas
* Good foundation in medicinal and synthetic chemistry with previous experience operating as a senior individual contributor within a pharma/biotech setting
* Experience in execution of drug discovery programs from HitID to Candidate delivery with a consistent track record, working in multidisciplinary teams
* Experience in a lead chemist role
* Experience of contributing to Structure-Based Drug Design problems
* Experience and expertise working on Lead Optimisation programs.
* Experience of working with and closely managing CRO resource
* Track record of authorship of relevant scientific manuscripts and inventorship of composition of matter patents.
Nice to have:
* Experience of new modalities or peptides
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