The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge wishes to appoint a post-doctoral Research Associate to join the research group of Prof. Edmund Kunji at the MRC Mitochondrial Biology Unit. A world-renowned centre for research, the MRC MBU is a vibrant community focused on the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases. Additional information can be found at www.mrc-mbu.cam.ac.uk. The post holder will work within a programme focused on mitochondrial transport proteins, which are crucial for the functioning of mammalian cells. This project is funded by Apollo Therapeutics and focusses on the development of specific inhibitors of a mitochondrial carrier protein. Thermostability shift and transport assays have already been developed to screen for better and more specific binders. The project involves a collaboration with Apollo Therapeutics and associated Contract Research Organizations as well as with different experts on mitochondrial biology within the MRC-MBU. The post-holder will participate in every stage of the process, including protein purification, screening of novel binders by thermostability shift and transport assays, structural analysis by cryo-EM, interaction with other team members and collaborators, and preparation of manuscripts/IP. The candidate for the Postdoctoral Research Associate position will have a PhD in Molecular Biology, Biochemistry, or related disciplines, and a track record of related research achievements. Extensive experience in membrane proteins and drug screening procedures is essential. The post holder will be collaborating closely with other members of the Kunji group as well as with Apollo and associated Contract Research Organizations. Several training opportunities on different aspects of mitochondrial biology will be provided. Informal enquiries about this position should be directed to Professor Edmund Kunji ( ersk2cam.ac.uk ). This is a fixed term post with funding available until 31 January 2026 in the first instance. Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Please include details of your referees, including email address and phone number, one of which must be your most recent line manager. The closing date for applications is: 19th January 2025 The interview date for the role is: To be confirmed Please quote reference SM44512 on your application and in any correspondence about this vacancy. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Further information Further Particulars Apply online